Selectively blocks cysteinyl leukotriene receptor 1 (CysLT1), preventing leukotriene D4-mediated bronchoconstriction, mucus secretion, vascular permeability, and eosinophil recruitment. Reduces airway inflammation without affecting COX pathway.
At a glance
Class
Leukotriene Receptor Antagonist
Storage
Store at room temperature, protect from moisture and light
Dosing
Off-label for chronic bronchitis, asthma, and eosinophilic airway disease
Off-label for feline asthma as adjunct to inhaled corticosteroids
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Safety
Respiratory responseGI tolerance
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Interactions
No documented interactions.
FAQs
Frequently asked questions
›What is Montelukast?
Montelukast is a leukotriene receptor antagonist used in pets. Selectively blocks cysteinyl leukotriene receptor 1 (CysLT1), preventing leukotriene D4-mediated bronchoconstriction, mucus secretion, vascular permeability, and eosinophil recruitment. Reduces airway inflammation without affecting COX pathway.
›What is Montelukast used for in pets?
Montelukast is used in veterinary medicine for: Off-label for chronic bronchitis, asthma, and eosinophilic airway disease; Off-label for feline asthma as adjunct to inhaled corticosteroids.
›What is the Montelukast dose for dogs?
For dogs, Montelukast is typically dosed as follows — Off-label for chronic bronchitis, asthma, and eosinophilic airway disease: 1–2 mg/kg PO q24h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Montelukast dose for cats?
For cats, Montelukast is typically dosed as follows — Off-label for feline asthma as adjunct to inhaled corticosteroids: 0.25–0.5 mg/kg PO q24h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›Does Montelukast need a prescription?
Yes. Montelukast is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →References
References
The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.
Textbooks & handbooks — 5
- Plumb's Veterinary Drug Handbook
- Withrow & MacEwen's Small Animal Clinical Oncology
- Merck Veterinary Manual
- NRC Nutrient Requirements of Dogs and Cats
- Veterinary Pharmacology and Therapeutics (Riviere & Papich)
Clinical guidelines & consensus — 4
- ASPCA Animal Poison Control Center Guidelines
- AAHA Diabetes Management Guidelines
- ASPCA Poison Control Guidelines
- RECOVER CPR Guidelines
Journals & peer-reviewed studies — 2
- EPIC Study (J Vet Intern Med 2016)
- JVIM FAT CAT Study
Regulatory & approvals — 1
- CDSCO Veterinary Drug Approval Registry (1969–2026)
Databases — 1
- Washington State University VCPL MDR1 Database