Sulfonamide-derived carbonic anhydrase inhibitor that reduces aqueous humor production in the ciliary body. Better CNS penetration and longer duration than acetazolamide. Less metabolic acidosis than dichlorphenamide.
At a glance
Class
Carbonic Anhydrase Inhibitor
Storage
Store at room temperature
Dosing
Used for glaucoma management — reduces IOP by decreasing aqueous humor productio
Same glaucoma indications
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Safety
IOPSerum electrolytesBlood gasRenal function
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Interactions
No documented interactions.
FAQs
Frequently asked questions
›What is Methazolamide?
Methazolamide is a carbonic anhydrase inhibitor used in pets. Sulfonamide-derived carbonic anhydrase inhibitor that reduces aqueous humor production in the ciliary body. Better CNS penetration and longer duration than acetazolamide. Less metabolic acidosis than dichlorphenamide.
›What is Methazolamide used for in pets?
Methazolamide is used in veterinary medicine for: Used for glaucoma management — reduces IOP by decreasing aqueous humor productio; Same glaucoma indications.
›What is the Methazolamide dose for dogs?
For dogs, Methazolamide is typically dosed as follows — Used for glaucoma management — reduces IOP by decreasing aqueous humor productio: 2–5 mg/kg PO q8–12h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Methazolamide dose for cats?
For cats, Methazolamide is typically dosed as follows — Same glaucoma indications: 2–5 mg/kg PO q8–12h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›Does Methazolamide need a prescription?
Yes. Methazolamide is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →References
References
The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.
Textbooks & handbooks — 5
- Plumb's Veterinary Drug Handbook
- Withrow & MacEwen's Small Animal Clinical Oncology
- Merck Veterinary Manual
- NRC Nutrient Requirements of Dogs and Cats
- Veterinary Pharmacology and Therapeutics (Riviere & Papich)
Clinical guidelines & consensus — 4
- ASPCA Animal Poison Control Center Guidelines
- AAHA Diabetes Management Guidelines
- ASPCA Poison Control Guidelines
- RECOVER CPR Guidelines
Journals & peer-reviewed studies — 2
- EPIC Study (J Vet Intern Med 2016)
- JVIM FAT CAT Study
Regulatory & approvals — 1
- CDSCO Veterinary Drug Approval Registry (1969–2026)
Databases — 1
- Washington State University VCPL MDR1 Database