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Metergoline

Prescription
Serotonin Antagonist / Prolactin Inhibitor
Last reviewed 22 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
1 available
Formulations
1

Mechanism of action

Ergoline derivative that antagonizes serotonin (5-HT2) receptors and inhibits prolactin secretion from the anterior pituitary. Reduces lactation and pseudopregnancy symptoms. Alternative to cabergoline and bromocriptine.

At a glance

Class
Serotonin Antagonist / Prolactin Inhibitor
Schedule
Prescription
Storage
Store at room temperature, protect from light

Dosing

🐕

Dog

Used for pseudopregnancy/pseudolactation
Dose
0.1–0.2 mg/kg
Route
PO
Frequency
q12h
🐈

Cat

Used for feline pseudolactation
Dose
0.1 mg/kg
Route
PO
Frequency
q12h
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Other — 1

Strength

Storage

Store at room temperature, protect from light

Safety

Monitoring parameters

Clinical resolution of pseudopregnancyGI tolerance
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

No documented interactions.

Brands

EU

Contralac

FAQs

Frequently asked questions

What is Metergoline?
Metergoline is a serotonin antagonist / prolactin inhibitor used in pets. Ergoline derivative that antagonizes serotonin (5-HT2) receptors and inhibits prolactin secretion from the anterior pituitary. Reduces lactation and pseudopregnancy symptoms. Alternative to cabergoline and bromocriptine.
What is Metergoline used for in pets?
Metergoline is used in veterinary medicine for: Used for pseudopregnancy/pseudolactation; Used for feline pseudolactation.
What is the Metergoline dose for dogs?
For dogs, Metergoline is typically dosed as follows — Used for pseudopregnancy/pseudolactation: 0.1–0.2 mg/kg PO q12h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Metergoline dose for cats?
For cats, Metergoline is typically dosed as follows — Used for feline pseudolactation: 0.1 mg/kg PO q12h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
Does Metergoline need a prescription?
Yes. Metergoline is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database
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