Intermediate-acting amide local anesthetic that blocks voltage-gated sodium channels, preventing nerve impulse conduction. Similar potency to lidocaine but longer duration (2–3h vs 1–1.5h) and less vasodilation (no epinephrine needed).
At a glance
Class
Amide Local Anesthetic
Storage
Store at room temperature, protect from light
Dosing
Used for dental nerve blocks (inferior alveolar, infraorbital, mental nerve bloc
Route
Local infiltration, Regional nerve block
Frequency
Single administration
Used for feline dental blocks and local anesthesia
Route
Local infiltration, Regional nerve block
Frequency
Single administration
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Safety
Total dose calculationSigns of systemic toxicity for 30 min post-administration
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Interactions
No documented interactions.
FAQs
Frequently asked questions
›What is Mepivacaine?
Mepivacaine is a amide local anesthetic used in pets. Intermediate-acting amide local anesthetic that blocks voltage-gated sodium channels, preventing nerve impulse conduction. Similar potency to lidocaine but longer duration (2–3h vs 1–1.5h) and less vasodilation (no epinephrine needed).
›What is Mepivacaine used for in pets?
Mepivacaine is used in veterinary medicine for: Used for dental nerve blocks (inferior alveolar, infraorbital, mental nerve bloc; Used for feline dental blocks and local anesthesia.
›What is the Mepivacaine dose for dogs?
For dogs, Mepivacaine is typically dosed as follows — Used for dental nerve blocks (inferior alveolar, infraorbital, mental nerve bloc: undefined undefined Local infiltration/Regional nerve block Single administration. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Mepivacaine dose for cats?
For cats, Mepivacaine is typically dosed as follows — Used for feline dental blocks and local anesthesia: undefined undefined Local infiltration/Regional nerve block Single administration. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›Does Mepivacaine need a prescription?
Yes. Mepivacaine is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →References
References
The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.
Textbooks & handbooks — 5
- Plumb's Veterinary Drug Handbook
- Withrow & MacEwen's Small Animal Clinical Oncology
- Merck Veterinary Manual
- NRC Nutrient Requirements of Dogs and Cats
- Veterinary Pharmacology and Therapeutics (Riviere & Papich)
Clinical guidelines & consensus — 4
- ASPCA Animal Poison Control Center Guidelines
- AAHA Diabetes Management Guidelines
- ASPCA Poison Control Guidelines
- RECOVER CPR Guidelines
Journals & peer-reviewed studies — 2
- EPIC Study (J Vet Intern Med 2016)
- JVIM FAT CAT Study
Regulatory & approvals — 1
- CDSCO Veterinary Drug Approval Registry (1969–2026)
Databases — 1
- Washington State University VCPL MDR1 Database