Soybean oil-based IV fat emulsion that acts as a 'lipid sink', sequestering lipophilic toxins (local anesthetics, calcium channel blockers, beta-blockers, ivermectin) within lipid droplets in plasma, reducing free drug concentration at target organs.
At a glance
Class
Lipid Rescue / Nutritional Supplement
Storage
Store at room temperature; do not freeze; use within 24h of opening; inspect for separation before use
Dosing
Used for lipophilic drug toxicity: bupivacaine/lidocaine cardiac toxicity, iverm
Frequency
See protocol — bolus + CRI
Particularly useful for permethrin toxicity in cats, ivermectin toxicity, and lo
Frequency
Same protocol as dogs
Safety
Clinical response to toxicityTriglycerides (expected to be elevated — clear in 4–6h)LactateElectrolytesNote: lab values unreliable during lipemia
Interactions
No documented interactions.
FAQs
Frequently asked questions
›What is Lipid Emulsion, Intravenous (ILE)?
Lipid Emulsion, Intravenous (ILE) is a lipid rescue / nutritional supplement used in pets. Soybean oil-based IV fat emulsion that acts as a 'lipid sink', sequestering lipophilic toxins (local anesthetics, calcium channel blockers, beta-blockers, ivermectin) within lipid droplets in plasma, reducing free drug concentration at target organs.
›What is Lipid Emulsion, Intravenous (ILE) used for in pets?
Lipid Emulsion, Intravenous (ILE) is used in veterinary medicine for: Used for lipophilic drug toxicity: bupivacaine/lidocaine cardiac toxicity, iverm; Particularly useful for permethrin toxicity in cats, ivermectin toxicity, and lo.
›What is the Lipid Emulsion, Intravenous (ILE) dose for dogs?
For dogs, Lipid Emulsion, Intravenous (ILE) is typically dosed as follows — Used for lipophilic drug toxicity: bupivacaine/lidocaine cardiac toxicity, iverm: undefined undefined IV (bolus + CRI) See protocol — bolus + CRI. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Lipid Emulsion, Intravenous (ILE) dose for cats?
For cats, Lipid Emulsion, Intravenous (ILE) is typically dosed as follows — Particularly useful for permethrin toxicity in cats, ivermectin toxicity, and lo: undefined undefined IV Same protocol as dogs. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›Does Lipid Emulsion, Intravenous (ILE) need a prescription?
Yes. Lipid Emulsion, Intravenous (ILE) is a prescription medication and should only be administered under veterinary supervision.
References
References
Textbooks & handbooks
- Plumb, D.C. Plumb's Veterinary Drug Handbook. 10th ed., Wiley-Blackwell, 2023.
- Vail, D.M., Thamm, D.H., & Liptak, J.M. (eds.). Withrow & MacEwen's Small Animal Clinical Oncology. 6th ed., Saunders/Elsevier, 2020.
- Riviere, J.E., & Papich, M.G. (eds.). Veterinary Pharmacology and Therapeutics. 10th ed., Wiley-Blackwell, 2018.
- National Research Council. Nutrient Requirements of Dogs and Cats. National Academies Press, Washington DC, 2006.
- The Merck Veterinary Manual. Merck & Co., Online edition. https://www.merckvetmanual.com/
Clinical guidelines & consensus
- Fletcher, D.J., Boller, M., Brainard, B.M., et al. "RECOVER Evidence and Knowledge Gap Analysis on Veterinary CPR." Journal of Veterinary Emergency and Critical Care, 2012;22(S1):S102–S131.
- American Animal Hospital Association. 2018 AAHA Diabetes Management Guidelines for Dogs and Cats. AAHA Press.
Journals & peer-reviewed studies
- Hogan, D.F., Fox, P.R., Jacob, K., et al. "Secondary prevention of cardiogenic arterial thromboembolism in the cat: The FAT CAT study." Journal of Veterinary Cardiology, 2015;17(Suppl 1):S306–S317.
- Boswood, A., Häggström, J., Gordon, S.G., et al. "Effect of Pimobendan in Dogs with Preclinical Myxomatous Mitral Valve Disease and Cardiomegaly: The EPIC Study — A Randomized Clinical Trial." Journal of Veterinary Internal Medicine, 2016;30(6):1765–1779.
- ASPCA Animal Poison Control Center. Toxicology and Poison Management Guidelines. American Society for the Prevention of Cruelty to Animals. https://www.aspca.org/pet-care/animal-poison-control
Regulatory & approvals
- Central Drugs Standard Control Organisation (CDSCO), Government of India. Veterinary Drug Approval Registry, 1969–2026. Directorate General of Health Services. https://cdsco.gov.in/
Databases
- Washington State University, College of Veterinary Medicine. Veterinary Clinical Pharmacology Laboratory (VCPL) — MDR1 Multidrug Sensitivity Database. https://vcpl.vetmed.wsu.edu/
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
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