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Levofloxacin Ophthalmic

Prescription
Ophthalmic Third-Generation Fluoroquinolone
Last reviewed 22 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
2 available
Formulations
2

Mechanism of action

L-isomer of ofloxacin with 2x greater potency. Inhibits both DNA gyrase and topoisomerase IV. Better gram-positive coverage than ciprofloxacin and ofloxacin. Good corneal and aqueous humor penetration.

At a glance

Class
Ophthalmic Third-Generation Fluoroquinolone
Schedule
Prescription
Storage
Store at room temperature

Dosing

🐕

Dog

Used for bacterial keratitis (1
Dose
Route
Ophthalmic
Frequency
q2–6h
🐈

Cat

Effective for bacterial conjunctivitis and keratitis
Dose
Route
Ophthalmic
Frequency
q4–6h
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Other — 2

Strength
Strength

Storage

Store at room temperature

Safety

Monitoring parameters

Clinical responseCulture and sensitivity for refractory cases
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

No documented interactions.

Brands

Other markets

Quixin
Iquix

FAQs

Frequently asked questions

What is Levofloxacin Ophthalmic?
Levofloxacin Ophthalmic is a ophthalmic third-generation fluoroquinolone used in pets. L-isomer of ofloxacin with 2x greater potency. Inhibits both DNA gyrase and topoisomerase IV. Better gram-positive coverage than ciprofloxacin and ofloxacin. Good corneal and aqueous humor penetration.
What is Levofloxacin Ophthalmic used for in pets?
Levofloxacin Ophthalmic is used in veterinary medicine for: Used for bacterial keratitis (1; Effective for bacterial conjunctivitis and keratitis.
What is the Levofloxacin Ophthalmic dose for dogs?
For dogs, Levofloxacin Ophthalmic is typically dosed as follows — Used for bacterial keratitis (1: undefined undefined Ophthalmic q2–6h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Levofloxacin Ophthalmic dose for cats?
For cats, Levofloxacin Ophthalmic is typically dosed as follows — Effective for bacterial conjunctivitis and keratitis: undefined undefined Ophthalmic q4–6h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
Does Levofloxacin Ophthalmic need a prescription?
Yes. Levofloxacin Ophthalmic is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database
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