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Levamisole

Prescription
Anthelmintic / Immunostimulant
Last reviewed 21 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
2 available
Formulations
3

Mechanism of action

Agonist at nicotinic acetylcholine receptors on nematode muscle, causing sustained contraction and paralysis. Also stimulates cell-mediated immunity (T-lymphocyte function) by mimicking thymic hormones — used as immunostimulant.

At a glance

Class
Anthelmintic / Immunostimulant
Schedule
Prescription
Storage
Store at room temperature below 30°C

Dosing

🐕

Dog

Anthelmintic use largely replaced by fenbendazole/pyrantel
Dose
5–8 mg/kg
Route
PO
Frequency
Once (anthelmintic); q48h (immunomodulator)
🐈

Cat

Cats are very sensitive to levamisole toxicity
Dose
Route
N, A
Frequency
N/A
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Other — 3

Strength
Strength
Strength

Storage

Store at room temperature below 30°C

Safety

Monitoring parameters

Neurological signsCBC with immunomodulatory useFecal exam post-treatment
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

No documented interactions.

Brands

Other markets

Levasol
Ergamisol

FAQs

Frequently asked questions

What is Levamisole?
Levamisole is a anthelmintic / immunostimulant used in pets. Agonist at nicotinic acetylcholine receptors on nematode muscle, causing sustained contraction and paralysis. Also stimulates cell-mediated immunity (T-lymphocyte function) by mimicking thymic hormones — used as immunostimulant.
What is Levamisole used for in pets?
Levamisole is used in veterinary medicine for: Anthelmintic use largely replaced by fenbendazole/pyrantel; Cats are very sensitive to levamisole toxicity.
What is the Levamisole dose for dogs?
For dogs, Levamisole is typically dosed as follows — Anthelmintic use largely replaced by fenbendazole/pyrantel: 5–8 mg/kg PO Once (anthelmintic); q48h (immunomodulator). Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Levamisole dose for cats?
For cats, Levamisole is typically dosed as follows — Cats are very sensitive to levamisole toxicity: undefined undefined N/A N/A. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
Does Levamisole need a prescription?
Yes. Levamisole is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

CDSCO approvals (India) — 5

Levamisole +oxyclozanide suspension
M/s Tebma Chemical Industries · Approved 29.09.1993
for veterinary use
Each 5 ml of the suspension contains: Levamisole HCl IP 112.5 mg eq to levamisol
M/s. Gopaldas & Vishramdas · Approved 07.08.2014
For control and treatment of Gastrointestinal and pulmonary Nematodes, liver Flukes and Amphistomes.
Levamisole hydrochloride IP 15.0% w/w Eq. to Levamisole 12.7% w/w + Anhydrous Co
M/s. Gopal Das Vishram & Co. Ltd · Approved 30.04.2015
For control and treatment of gastrointestinal and pulmonary nematodes
Levamisole HCl IP 2.0gm + Oxyclozanide IP 4.0gm (veterinary product) (Additional
M/s. Akums Drugs & Pharmaceuticals Ltd · Approved 08.06.2015
For the treatment of all flukes (Fasciola spp) & Tapeworm segmnts (Moniezia spp.) for cattle and sheep. Also for the var
Each Bolus (Tablet) contains: Levamisole HCl IP 1.5 g eq to levamisole 1.27 g +
M/s. VIBRO PHARMA · Approved 21.08.2015
For control and treatment of Gastrointestinal and pulmonary Nematodes, liver Flukes and Amphistomes.
Source: CDSCO Veterinary Drug Approval Registry (1969–2026)

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database
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