Prostaglandin F2α analog that activates FP prostanoid receptors in the ciliary body, increasing uveoscleral aqueous outflow (alternative drainage pathway) by remodeling extracellular matrix. Most potent single-agent IOP reducer (~30–50% reduction).
At a glance
Class
Ophthalmic Prostaglandin Analog (FP Receptor Agonist)
Storage
Refrigerate unopened; in-use at room temperature up to 6 weeks; protect from light
Dosing
First-line for canine glaucoma — most potent topical IOP reducer
Cats show inconsistent response to prostaglandin analogs
Safety
IOP at 1–2h post-dose initially, then q2–4 weeksSigns of uveitisPupil size
Interactions
No documented interactions.
FAQs
Frequently asked questions
›What is Latanoprost Ophthalmic?
Latanoprost Ophthalmic is a ophthalmic prostaglandin analog (fp receptor agonist) used in pets. Prostaglandin F2α analog that activates FP prostanoid receptors in the ciliary body, increasing uveoscleral aqueous outflow (alternative drainage pathway) by remodeling extracellular matrix. Most potent single-agent IOP reducer (~30–50% reduction).
›What is Latanoprost Ophthalmic used for in pets?
Latanoprost Ophthalmic is used in veterinary medicine for: First-line for canine glaucoma — most potent topical IOP reducer; Cats show inconsistent response to prostaglandin analogs.
›What is the Latanoprost Ophthalmic dose for dogs?
For dogs, Latanoprost Ophthalmic is typically dosed as follows — First-line for canine glaucoma — most potent topical IOP reducer: undefined undefined Ophthalmic q12–24h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Latanoprost Ophthalmic dose for cats?
For cats, Latanoprost Ophthalmic is typically dosed as follows — Cats show inconsistent response to prostaglandin analogs: undefined undefined Ophthalmic q12–24h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›Does Latanoprost Ophthalmic need a prescription?
Yes. Latanoprost Ophthalmic is a prescription medication and should only be administered under veterinary supervision.
References
References
Textbooks & handbooks
- Plumb, D.C. Plumb's Veterinary Drug Handbook. 10th ed., Wiley-Blackwell, 2023.
- Vail, D.M., Thamm, D.H., & Liptak, J.M. (eds.). Withrow & MacEwen's Small Animal Clinical Oncology. 6th ed., Saunders/Elsevier, 2020.
- Riviere, J.E., & Papich, M.G. (eds.). Veterinary Pharmacology and Therapeutics. 10th ed., Wiley-Blackwell, 2018.
- National Research Council. Nutrient Requirements of Dogs and Cats. National Academies Press, Washington DC, 2006.
- The Merck Veterinary Manual. Merck & Co., Online edition. https://www.merckvetmanual.com/
Clinical guidelines & consensus
- Fletcher, D.J., Boller, M., Brainard, B.M., et al. "RECOVER Evidence and Knowledge Gap Analysis on Veterinary CPR." Journal of Veterinary Emergency and Critical Care, 2012;22(S1):S102–S131.
- American Animal Hospital Association. 2018 AAHA Diabetes Management Guidelines for Dogs and Cats. AAHA Press.
Journals & peer-reviewed studies
- Hogan, D.F., Fox, P.R., Jacob, K., et al. "Secondary prevention of cardiogenic arterial thromboembolism in the cat: The FAT CAT study." Journal of Veterinary Cardiology, 2015;17(Suppl 1):S306–S317.
- Boswood, A., Häggström, J., Gordon, S.G., et al. "Effect of Pimobendan in Dogs with Preclinical Myxomatous Mitral Valve Disease and Cardiomegaly: The EPIC Study — A Randomized Clinical Trial." Journal of Veterinary Internal Medicine, 2016;30(6):1765–1779.
- ASPCA Animal Poison Control Center. Toxicology and Poison Management Guidelines. American Society for the Prevention of Cruelty to Animals. https://www.aspca.org/pet-care/animal-poison-control
Regulatory & approvals
- Central Drugs Standard Control Organisation (CDSCO), Government of India. Veterinary Drug Approval Registry, 1969–2026. Directorate General of Health Services. https://cdsco.gov.in/
Databases
- Washington State University, College of Veterinary Medicine. Veterinary Clinical Pharmacology Laboratory (VCPL) — MDR1 Multidrug Sensitivity Database. https://vcpl.vetmed.wsu.edu/
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
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