Acylated insulin analog with a 14-carbon fatty acid chain (myristic acid) attached to B29 lysine, enabling albumin binding (>98%) in SQ tissue and plasma. Slow dissociation from albumin provides prolonged, relatively peakless basal insulin release.
At a glance
Class
Long-Acting Basal Insulin Analog
Storage
Refrigerate unopened 2–8°C; in-use at room temperature up to 42 days; do not freeze
Dosing
Alternative long-acting insulin for dogs with poor response to NPH
Excellent option for feline diabetes — comparable remission rates to glargine
Safety
Blood glucose curves q7–14 days during adjustmentFructosamine q2–4 weeksBody weightSigns of hypoglycemia
Interactions
No documented interactions.
FAQs
Frequently asked questions
›What is Insulin, Detemir?
Insulin, Detemir is a long-acting basal insulin analog used in pets. Acylated insulin analog with a 14-carbon fatty acid chain (myristic acid) attached to B29 lysine, enabling albumin binding (>98%) in SQ tissue and plasma. Slow dissociation from albumin provides prolonged, relatively peakless basal insulin release.
›What is Insulin, Detemir used for in pets?
Insulin, Detemir is used in veterinary medicine for: Alternative long-acting insulin for dogs with poor response to NPH; Excellent option for feline diabetes — comparable remission rates to glargine.
›What is the Insulin, Detemir dose for dogs?
For dogs, Insulin, Detemir is typically dosed as follows — Alternative long-acting insulin for dogs with poor response to NPH: 0.1–0.2 U/kg SQ q12h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Insulin, Detemir dose for cats?
For cats, Insulin, Detemir is typically dosed as follows — Excellent option for feline diabetes — comparable remission rates to glargine: undefined undefined SQ q12h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›Does Insulin, Detemir need a prescription?
Yes. Insulin, Detemir is a prescription medication and should only be administered under veterinary supervision.
References
References
Textbooks & handbooks
- Plumb, D.C. Plumb's Veterinary Drug Handbook. 10th ed., Wiley-Blackwell, 2023.
- Vail, D.M., Thamm, D.H., & Liptak, J.M. (eds.). Withrow & MacEwen's Small Animal Clinical Oncology. 6th ed., Saunders/Elsevier, 2020.
- Riviere, J.E., & Papich, M.G. (eds.). Veterinary Pharmacology and Therapeutics. 10th ed., Wiley-Blackwell, 2018.
- National Research Council. Nutrient Requirements of Dogs and Cats. National Academies Press, Washington DC, 2006.
- The Merck Veterinary Manual. Merck & Co., Online edition. https://www.merckvetmanual.com/
Clinical guidelines & consensus
- Fletcher, D.J., Boller, M., Brainard, B.M., et al. "RECOVER Evidence and Knowledge Gap Analysis on Veterinary CPR." Journal of Veterinary Emergency and Critical Care, 2012;22(S1):S102–S131.
- American Animal Hospital Association. 2018 AAHA Diabetes Management Guidelines for Dogs and Cats. AAHA Press.
Journals & peer-reviewed studies
- Hogan, D.F., Fox, P.R., Jacob, K., et al. "Secondary prevention of cardiogenic arterial thromboembolism in the cat: The FAT CAT study." Journal of Veterinary Cardiology, 2015;17(Suppl 1):S306–S317.
- Boswood, A., Häggström, J., Gordon, S.G., et al. "Effect of Pimobendan in Dogs with Preclinical Myxomatous Mitral Valve Disease and Cardiomegaly: The EPIC Study — A Randomized Clinical Trial." Journal of Veterinary Internal Medicine, 2016;30(6):1765–1779.
- ASPCA Animal Poison Control Center. Toxicology and Poison Management Guidelines. American Society for the Prevention of Cruelty to Animals. https://www.aspca.org/pet-care/animal-poison-control
Regulatory & approvals
- Central Drugs Standard Control Organisation (CDSCO), Government of India. Veterinary Drug Approval Registry, 1969–2026. Directorate General of Health Services. https://cdsco.gov.in/
Databases
- Washington State University, College of Veterinary Medicine. Veterinary Clinical Pharmacology Laboratory (VCPL) — MDR1 Multidrug Sensitivity Database. https://vcpl.vetmed.wsu.edu/
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
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