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Immune Globulin, Intravenous (IVIG)

Prescription
Human Polyclonal Immunoglobulin
Last reviewed 21 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
3 available
Formulations
2

Mechanism of action

Pooled human IgG from thousands of donors providing broad-spectrum passive immunity and immunomodulation. Mechanisms include Fc receptor blockade (preventing platelet/RBC destruction in ITP/IMHA), anti-idiotype antibody neutralization, complement inhibition, and cytokine modulation.

At a glance

Class
Human Polyclonal Immunoglobulin
Schedule
Prescription
Storage
Refrigerate 2–8°C; some products can be stored at room temperature per label; do not freeze; do not shake

Dosing

🐕

Dog

Used for IMHA, ITP, immune-mediated skin disease (pemphigus), myasthenia gravis
Dose
Route
kg, h, increase to max 2 mL, kg, h)
Frequency
Once; may repeat once
🐈

Cat

Same indications as dogs
Dose
Route
IV
Frequency
Once; may repeat once
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Other — 2

Strength
Strength

Storage

Refrigerate 2–8°C; some products can be stored at room temperature per label; do not freeze; do not shake

Safety

Monitoring parameters

Vital signs q15 min during infusionPlatelet count (ITP — expect rise in 1–3 days)PCV (IMHA)Renal functionSigns of anaphylaxis
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

No documented interactions.

Brands

Other markets

Gammagard
Privigen
Octagam

FAQs

Frequently asked questions

What is Immune Globulin, Intravenous (IVIG)?
Immune Globulin, Intravenous (IVIG) is a human polyclonal immunoglobulin used in pets. Pooled human IgG from thousands of donors providing broad-spectrum passive immunity and immunomodulation. Mechanisms include Fc receptor blockade (preventing platelet/RBC destruction in ITP/IMHA), anti-idiotype antibody neutralization, complement inhibition, and cytokine modulation.
What is Immune Globulin, Intravenous (IVIG) used for in pets?
Immune Globulin, Intravenous (IVIG) is used in veterinary medicine for: Used for IMHA, ITP, immune-mediated skin disease (pemphigus), myasthenia gravis ; Same indications as dogs.
What is the Immune Globulin, Intravenous (IVIG) dose for dogs?
For dogs, Immune Globulin, Intravenous (IVIG) is typically dosed as follows — Used for IMHA, ITP, immune-mediated skin disease (pemphigus), myasthenia gravis : undefined undefined kg/h/increase to max 2 mL/kg/h) Once; may repeat once. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Immune Globulin, Intravenous (IVIG) dose for cats?
For cats, Immune Globulin, Intravenous (IVIG) is typically dosed as follows — Same indications as dogs: undefined undefined IV Once; may repeat once. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
Does Immune Globulin, Intravenous (IVIG) need a prescription?
Yes. Immune Globulin, Intravenous (IVIG) is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database
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