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Imidapril

Prescription
ACE Inhibitor
Last reviewed 21 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
1 available
Formulations
1

Mechanism of action

Prodrug hydrolyzed to active metabolite imidaprilat which inhibits angiotensin-converting enzyme. Reduces angiotensin II and aldosterone, decreasing afterload, preload, and cardiac remodeling. Licensed for veterinary use in some countries.

At a glance

Class
ACE Inhibitor
Schedule
Prescription
Storage
Store at room temperature below 30°C

Dosing

🐕

Dog

Licensed in Europe/Australia for CHF in dogs
Dose
0.25 mg/kg
Route
PO
Frequency
q24h
🐈

Cat

Benazepril is preferred in feline CKD due to dual elimination
Dose
Route
PO
Frequency
N/A
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Other — 1

Strength

Storage

Store at room temperature below 30°C

Safety

Monitoring parameters

Blood pressureBUN/creatinineSerum potassiumClinical response
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

No documented interactions.

Brands

Other markets

Prilium

FAQs

Frequently asked questions

What is Imidapril?
Imidapril is a ace inhibitor used in pets. Prodrug hydrolyzed to active metabolite imidaprilat which inhibits angiotensin-converting enzyme. Reduces angiotensin II and aldosterone, decreasing afterload, preload, and cardiac remodeling. Licensed for veterinary use in some countries.
What is Imidapril used for in pets?
Imidapril is used in veterinary medicine for: Licensed in Europe/Australia for CHF in dogs; Benazepril is preferred in feline CKD due to dual elimination.
What is the Imidapril dose for dogs?
For dogs, Imidapril is typically dosed as follows — Licensed in Europe/Australia for CHF in dogs: 0.25 mg/kg PO q24h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Imidapril dose for cats?
For cats, Imidapril is typically dosed as follows — Benazepril is preferred in feline CKD due to dual elimination: undefined undefined PO N/A. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
Does Imidapril need a prescription?
Yes. Imidapril is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database

Related medicines

Other medicines in the same class (ACE Inhibitor).

Lisinopril
Rx
Lysine analog of enalaprilat that directly inhibits angiotensin-converting enzyme (ACE), reducing angiotensin II and aldosterone production without requiring hepatic activation (unlike enalapril). Reduces afterload, preload, and cardiac remodeling.
dogcat
Ramipril
Rx
Prodrug converted to ramiprilat; inhibits angiotensin-converting enzyme, reducing angiotensin II production, decreasing aldosterone secretion, and lowering systemic vascular resistance
dogcat
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