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Imepitoin

Prescription
Low-Affinity Partial Benzodiazepine Agonist / Anticonvulsant
Last reviewed 21 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
1 available
Formulations
1

Mechanism of action

Partial agonist at the benzodiazepine binding site of GABA-A receptors, with lower intrinsic efficacy than full benzodiazepines (less sedation, less tolerance, less dependence). Also weakly inhibits voltage-gated calcium channels.

At a glance

Class
Low-Affinity Partial Benzodiazepine Agonist / Anticonvulsant
Schedule
Prescription
Storage
Store at room temperature below 30°C

Dosing

🐕

Dog

Licensed for canine idiopathic epilepsy in EU (not FDA-approved in USA)
Dose
10–30 mg/kg
Route
PO
Frequency
q12h
🐈

Cat

Not licensed for cats
Dose
Route
PO
Frequency
N/A
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Other — 1

Strength

Storage

Store at room temperature below 30°C

Safety

Monitoring parameters

Seizure frequency diaryBody weight (polyphagia risk)Hepatic enzymes with prolonged use
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

No documented interactions.

Brands

Other markets

Pexion

FAQs

Frequently asked questions

What is Imepitoin?
Imepitoin is a low-affinity partial benzodiazepine agonist / anticonvulsant used in pets. Partial agonist at the benzodiazepine binding site of GABA-A receptors, with lower intrinsic efficacy than full benzodiazepines (less sedation, less tolerance, less dependence). Also weakly inhibits voltage-gated calcium channels.
What is Imepitoin used for in pets?
Imepitoin is used in veterinary medicine for: Licensed for canine idiopathic epilepsy in EU (not FDA-approved in USA); Not licensed for cats.
What is the Imepitoin dose for dogs?
For dogs, Imepitoin is typically dosed as follows — Licensed for canine idiopathic epilepsy in EU (not FDA-approved in USA): 10–30 mg/kg PO q12h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Imepitoin dose for cats?
For cats, Imepitoin is typically dosed as follows — Not licensed for cats: undefined undefined PO N/A. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
Does Imepitoin need a prescription?
Yes. Imepitoin is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database
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