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Glycerin (Glycerol), Oral

Prescription
Osmotic Agent / IOP-Lowering Agent
Last reviewed 21 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
1 available
Formulations
2

Mechanism of action

Osmotically active polyol alcohol that increases plasma osmolality after oral administration, drawing water from the vitreous humor and reducing intraocular pressure. Also used as an osmotic diuretic. Not metabolized to glucose (safe in diabetics).

At a glance

Class
Osmotic Agent / IOP-Lowering Agent
Schedule
Prescription
Storage
Store at room temperature; do not freeze

Dosing

🐕

Dog

Emergency IOP reduction for acute glaucoma while awaiting definitive treatment
Dose
1–2 mL/kg
Route
PO
Frequency
q8h (short-term only)
🐈

Cat

Same acute glaucoma indication
Dose
1–2 mL/kg
Route
PO
Frequency
q8h (short-term)
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Other — 2

Strength
Strength

Storage

Store at room temperature; do not freeze

Safety

Monitoring parameters

IOP measurementHydration statusSerum osmolalityElectrolytes
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

No documented interactions.

Brands

Other markets

Osmoglyn

FAQs

Frequently asked questions

What is Glycerin (Glycerol), Oral?
Glycerin (Glycerol), Oral is a osmotic agent / iop-lowering agent used in pets. Osmotically active polyol alcohol that increases plasma osmolality after oral administration, drawing water from the vitreous humor and reducing intraocular pressure. Also used as an osmotic diuretic. Not metabolized to glucose (safe in diabetics).
What is Glycerin (Glycerol), Oral used for in pets?
Glycerin (Glycerol), Oral is used in veterinary medicine for: Emergency IOP reduction for acute glaucoma while awaiting definitive treatment; Same acute glaucoma indication.
What is the Glycerin (Glycerol), Oral dose for dogs?
For dogs, Glycerin (Glycerol), Oral is typically dosed as follows — Emergency IOP reduction for acute glaucoma while awaiting definitive treatment: 1–2 mL/kg PO q8h (short-term only). Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Glycerin (Glycerol), Oral dose for cats?
For cats, Glycerin (Glycerol), Oral is typically dosed as follows — Same acute glaucoma indication: 1–2 mL/kg PO q8h (short-term). Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
Does Glycerin (Glycerol), Oral need a prescription?
Yes. Glycerin (Glycerol), Oral is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database
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