Amino monosaccharide that serves as a substrate for glycosaminoglycan and proteoglycan synthesis in cartilage matrix. May inhibit cartilage-degrading enzymes and reduce inflammatory cytokines (IL-1β, TNF-α). Evidence for clinical benefit in OA is mixed but widely used.
At a glance
Class
Chondroprotective Nutraceutical
Storage
Store in cool, dry place below 25°C; protect from moisture
Dosing
Most commonly combined with chondroitin sulfate and/or ASU (avocado-soybean unsa
Used for feline OA management
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Safety
Lameness/pain scores at 6–8 weeksBlood glucose in diabetic patients
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Interactions
No documented interactions.
FAQs
Frequently asked questions
›What is Glucosamine Hydrochloride?
Glucosamine Hydrochloride is a chondroprotective nutraceutical used in pets. Amino monosaccharide that serves as a substrate for glycosaminoglycan and proteoglycan synthesis in cartilage matrix. May inhibit cartilage-degrading enzymes and reduce inflammatory cytokines (IL-1β, TNF-α). Evidence for clinical benefit in OA is mixed but widely used.
›What is Glucosamine Hydrochloride used for in pets?
Glucosamine Hydrochloride is used in veterinary medicine for: Most commonly combined with chondroitin sulfate and/or ASU (avocado-soybean unsa; Used for feline OA management.
›What is the Glucosamine Hydrochloride dose for dogs?
For dogs, Glucosamine Hydrochloride is typically dosed as follows — Most commonly combined with chondroitin sulfate and/or ASU (avocado-soybean unsa: undefined undefined PO q12–24h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Glucosamine Hydrochloride dose for cats?
For cats, Glucosamine Hydrochloride is typically dosed as follows — Used for feline OA management: 125–250 mg PO q24h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›Does Glucosamine Hydrochloride need a prescription?
Glucosamine Hydrochloride is available over the counter. Even so, you should consult your veterinarian before giving any medication to your pet.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →References
References
The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.
Textbooks & handbooks — 5
- Plumb's Veterinary Drug Handbook
- Withrow & MacEwen's Small Animal Clinical Oncology
- Merck Veterinary Manual
- NRC Nutrient Requirements of Dogs and Cats
- Veterinary Pharmacology and Therapeutics (Riviere & Papich)
Clinical guidelines & consensus — 4
- ASPCA Animal Poison Control Center Guidelines
- AAHA Diabetes Management Guidelines
- ASPCA Poison Control Guidelines
- RECOVER CPR Guidelines
Journals & peer-reviewed studies — 2
- EPIC Study (J Vet Intern Med 2016)
- JVIM FAT CAT Study
Regulatory & approvals — 1
- CDSCO Veterinary Drug Approval Registry (1969–2026)
Databases — 1
- Washington State University VCPL MDR1 Database