Felinized monoclonal antibody that binds and neutralizes nerve growth factor (NGF), a key mediator of OA pain signaling. Prevents NGF from binding TrkA receptors on sensory neurons, reducing pain transmission.
At a glance
Class
Anti-NGF Monoclonal Antibody
Storage
Refrigerate 2–8°C; do not freeze; can be at room temperature up to 30 days
Dosing
FDA-approved for OA pain in cats
Frequency
Monthly (q28 days)
Safety
Pain and mobility scores at 4 weeksInjection site assessmentOwner satisfaction
Interactions
No documented interactions.
FAQs
Frequently asked questions
›What is Frunevetmab?
Frunevetmab is a anti-ngf monoclonal antibody used in pets. Felinized monoclonal antibody that binds and neutralizes nerve growth factor (NGF), a key mediator of OA pain signaling. Prevents NGF from binding TrkA receptors on sensory neurons, reducing pain transmission.
›What is Frunevetmab used for in pets?
Frunevetmab is used in veterinary medicine for: Frunevetmab is felinized; FDA-approved for OA pain in cats.
›What is the Frunevetmab dose for dogs?
For dogs, Frunevetmab is typically dosed as follows — Frunevetmab is felinized: undefined undefined N/A N/A. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Frunevetmab dose for cats?
For cats, Frunevetmab is typically dosed as follows — FDA-approved for OA pain in cats: 1–2.8 mg/kg SQ Monthly (q28 days). Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›Does Frunevetmab need a prescription?
Yes. Frunevetmab is a prescription medication and should only be administered under veterinary supervision.
References
References
Textbooks & handbooks
- Plumb, D.C. Plumb's Veterinary Drug Handbook. 10th ed., Wiley-Blackwell, 2023.
- Vail, D.M., Thamm, D.H., & Liptak, J.M. (eds.). Withrow & MacEwen's Small Animal Clinical Oncology. 6th ed., Saunders/Elsevier, 2020.
- Riviere, J.E., & Papich, M.G. (eds.). Veterinary Pharmacology and Therapeutics. 10th ed., Wiley-Blackwell, 2018.
- National Research Council. Nutrient Requirements of Dogs and Cats. National Academies Press, Washington DC, 2006.
- The Merck Veterinary Manual. Merck & Co., Online edition. https://www.merckvetmanual.com/
Clinical guidelines & consensus
- Fletcher, D.J., Boller, M., Brainard, B.M., et al. "RECOVER Evidence and Knowledge Gap Analysis on Veterinary CPR." Journal of Veterinary Emergency and Critical Care, 2012;22(S1):S102–S131.
- American Animal Hospital Association. 2018 AAHA Diabetes Management Guidelines for Dogs and Cats. AAHA Press.
Journals & peer-reviewed studies
- Hogan, D.F., Fox, P.R., Jacob, K., et al. "Secondary prevention of cardiogenic arterial thromboembolism in the cat: The FAT CAT study." Journal of Veterinary Cardiology, 2015;17(Suppl 1):S306–S317.
- Boswood, A., Häggström, J., Gordon, S.G., et al. "Effect of Pimobendan in Dogs with Preclinical Myxomatous Mitral Valve Disease and Cardiomegaly: The EPIC Study — A Randomized Clinical Trial." Journal of Veterinary Internal Medicine, 2016;30(6):1765–1779.
- ASPCA Animal Poison Control Center. Toxicology and Poison Management Guidelines. American Society for the Prevention of Cruelty to Animals. https://www.aspca.org/pet-care/animal-poison-control
Regulatory & approvals
- Central Drugs Standard Control Organisation (CDSCO), Government of India. Veterinary Drug Approval Registry, 1969–2026. Directorate General of Health Services. https://cdsco.gov.in/
Databases
- Washington State University, College of Veterinary Medicine. Veterinary Clinical Pharmacology Laboratory (VCPL) — MDR1 Multidrug Sensitivity Database. https://vcpl.vetmed.wsu.edu/
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →