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Frunevetmab

Prescription
Anti-NGF Monoclonal Antibody
Last reviewed 21 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
1 available
Formulations
1

Mechanism of action

Felinized monoclonal antibody that binds and neutralizes nerve growth factor (NGF), a key mediator of OA pain signaling. Prevents NGF from binding TrkA receptors on sensory neurons, reducing pain transmission.

At a glance

Class
Anti-NGF Monoclonal Antibody
Schedule
Prescription
Storage
Refrigerate 2–8°C; do not freeze; can be at room temperature up to 30 days

Dosing

🐕

Dog

Frunevetmab is felinized
Dose
Route
N, A
Frequency
N/A
🐈

Cat

FDA-approved for OA pain in cats
Dose
1–2.8 mg/kg
Route
SQ
Frequency
Monthly (q28 days)
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Other — 1

Strength

Storage

Refrigerate 2–8°C; do not freeze; can be at room temperature up to 30 days

Safety

Monitoring parameters

Pain and mobility scores at 4 weeksInjection site assessmentOwner satisfaction
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

No documented interactions.

Brands

Other markets

Solensia

FAQs

Frequently asked questions

What is Frunevetmab?
Frunevetmab is a anti-ngf monoclonal antibody used in pets. Felinized monoclonal antibody that binds and neutralizes nerve growth factor (NGF), a key mediator of OA pain signaling. Prevents NGF from binding TrkA receptors on sensory neurons, reducing pain transmission.
What is Frunevetmab used for in pets?
Frunevetmab is used in veterinary medicine for: Frunevetmab is felinized; FDA-approved for OA pain in cats.
What is the Frunevetmab dose for dogs?
For dogs, Frunevetmab is typically dosed as follows — Frunevetmab is felinized: undefined undefined N/A N/A. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Frunevetmab dose for cats?
For cats, Frunevetmab is typically dosed as follows — FDA-approved for OA pain in cats: 1–2.8 mg/kg SQ Monthly (q28 days). Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
Does Frunevetmab need a prescription?
Yes. Frunevetmab is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database
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