Inhibits the first step of bacterial cell wall synthesis by blocking MurA (UDP-N-acetylglucosamine enolpyruvyl transferase), which catalyzes peptidoglycan precursor formation. Unique mechanism — no cross-resistance with any other antibiotic class. Active against MDR organisms.
At a glance
Class
Phosphonic Acid Antibiotic
Storage
Store at room temperature below 30°C
Dosing
Reserved for multidrug-resistant UTIs (ESBL-producing E
Used for MDR UTIs in cats
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Safety
Urine culture pre- and post-treatmentClinical responseRenal function
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Interactions
No documented interactions.
FAQs
Frequently asked questions
›What is Fosfomycin?
Fosfomycin is a phosphonic acid antibiotic used in pets. Inhibits the first step of bacterial cell wall synthesis by blocking MurA (UDP-N-acetylglucosamine enolpyruvyl transferase), which catalyzes peptidoglycan precursor formation. Unique mechanism — no cross-resistance with any other antibiotic class. Active against MDR organisms.
›What is Fosfomycin used for in pets?
Fosfomycin is used in veterinary medicine for: Reserved for multidrug-resistant UTIs (ESBL-producing E; Used for MDR UTIs in cats.
›What is the Fosfomycin dose for dogs?
For dogs, Fosfomycin is typically dosed as follows — Reserved for multidrug-resistant UTIs (ESBL-producing E: 40–80 mg/kg PO/IV q8–12h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Fosfomycin dose for cats?
For cats, Fosfomycin is typically dosed as follows — Used for MDR UTIs in cats: 30–50 mg/kg PO q12h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›Does Fosfomycin need a prescription?
Yes. Fosfomycin is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →References
References
The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.
Textbooks & handbooks — 5
- Plumb's Veterinary Drug Handbook
- Withrow & MacEwen's Small Animal Clinical Oncology
- Merck Veterinary Manual
- NRC Nutrient Requirements of Dogs and Cats
- Veterinary Pharmacology and Therapeutics (Riviere & Papich)
Clinical guidelines & consensus — 4
- ASPCA Animal Poison Control Center Guidelines
- AAHA Diabetes Management Guidelines
- ASPCA Poison Control Guidelines
- RECOVER CPR Guidelines
Journals & peer-reviewed studies — 2
- EPIC Study (J Vet Intern Med 2016)
- JVIM FAT CAT Study
Regulatory & approvals — 1
- CDSCO Veterinary Drug Approval Registry (1969–2026)
Databases — 1
- Washington State University VCPL MDR1 Database