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Fluorescein Stain Ophthalmic

Ophthalmic Diagnostic Dye
Last reviewed 22 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
2 available
Formulations
2

Mechanism of action

Hydrophilic fluorescent dye that pools in areas of corneal epithelial loss (ulcers, erosions) but does not stain intact epithelium. Under cobalt blue light, fluorescein-stained areas fluoresce bright green, delineating the extent of corneal damage.

At a glance

Class
Ophthalmic Diagnostic Dye
Schedule
OTC
Storage
Store at room temperature; strips in sealed foil packets; solution — single-use, discard after opening

Dosing

🐕

Dog

ESSENTIAL diagnostic tool for every eye exam
Dose
Route
Ophthalmic
Frequency
Single diagnostic application
🐈

Cat

Same importance in feline ophthalmology
Dose
Route
Ophthalmic
Frequency
Single diagnostic application

Formulations

💊

Other — 2

Strength
Strength

Storage

Store at room temperature; strips in sealed foil packets; solution — single-use, discard after opening

Safety

Monitoring parameters

Corneal staining pattern (positive = ulcer; negative = intact epithelium)Seidel test (streaming = full-thickness perforation/leak)

Interactions

No documented interactions.

Brands

Other markets

Fluor-I-Strip
Ful-Glo

FAQs

Frequently asked questions

What is Fluorescein Stain Ophthalmic?
Fluorescein Stain Ophthalmic is a ophthalmic diagnostic dye used in pets. Hydrophilic fluorescent dye that pools in areas of corneal epithelial loss (ulcers, erosions) but does not stain intact epithelium. Under cobalt blue light, fluorescein-stained areas fluoresce bright green, delineating the extent of corneal damage.
What is Fluorescein Stain Ophthalmic used for in pets?
Fluorescein Stain Ophthalmic is used in veterinary medicine for: ESSENTIAL diagnostic tool for every eye exam; Same importance in feline ophthalmology.
What is the Fluorescein Stain Ophthalmic dose for dogs?
For dogs, Fluorescein Stain Ophthalmic is typically dosed as follows — ESSENTIAL diagnostic tool for every eye exam: undefined undefined Ophthalmic Single diagnostic application. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Fluorescein Stain Ophthalmic dose for cats?
For cats, Fluorescein Stain Ophthalmic is typically dosed as follows — Same importance in feline ophthalmology: undefined undefined Ophthalmic Single diagnostic application. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
Does Fluorescein Stain Ophthalmic need a prescription?
Fluorescein Stain Ophthalmic is available over the counter. Even so, you should consult your veterinarian before giving any medication to your pet.

References

References

Textbooks & handbooks

  • Plumb, D.C. Plumb's Veterinary Drug Handbook. 10th ed., Wiley-Blackwell, 2023.
  • Vail, D.M., Thamm, D.H., & Liptak, J.M. (eds.). Withrow & MacEwen's Small Animal Clinical Oncology. 6th ed., Saunders/Elsevier, 2020.
  • Riviere, J.E., & Papich, M.G. (eds.). Veterinary Pharmacology and Therapeutics. 10th ed., Wiley-Blackwell, 2018.
  • National Research Council. Nutrient Requirements of Dogs and Cats. National Academies Press, Washington DC, 2006.
  • The Merck Veterinary Manual. Merck & Co., Online edition. https://www.merckvetmanual.com/

Clinical guidelines & consensus

  • Fletcher, D.J., Boller, M., Brainard, B.M., et al. "RECOVER Evidence and Knowledge Gap Analysis on Veterinary CPR." Journal of Veterinary Emergency and Critical Care, 2012;22(S1):S102–S131.
  • American Animal Hospital Association. 2018 AAHA Diabetes Management Guidelines for Dogs and Cats. AAHA Press.

Journals & peer-reviewed studies

  • Hogan, D.F., Fox, P.R., Jacob, K., et al. "Secondary prevention of cardiogenic arterial thromboembolism in the cat: The FAT CAT study." Journal of Veterinary Cardiology, 2015;17(Suppl 1):S306–S317.
  • Boswood, A., Häggström, J., Gordon, S.G., et al. "Effect of Pimobendan in Dogs with Preclinical Myxomatous Mitral Valve Disease and Cardiomegaly: The EPIC Study — A Randomized Clinical Trial." Journal of Veterinary Internal Medicine, 2016;30(6):1765–1779.
  • ASPCA Animal Poison Control Center. Toxicology and Poison Management Guidelines. American Society for the Prevention of Cruelty to Animals. https://www.aspca.org/pet-care/animal-poison-control

Regulatory & approvals

  • Central Drugs Standard Control Organisation (CDSCO), Government of India. Veterinary Drug Approval Registry, 1969–2026. Directorate General of Health Services. https://cdsco.gov.in/

Databases

  • Washington State University, College of Veterinary Medicine. Veterinary Clinical Pharmacology Laboratory (VCPL) — MDR1 Multidrug Sensitivity Database. https://vcpl.vetmed.wsu.edu/
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Related medicines

Other medicines in the same class (Ophthalmic Diagnostic Dye).

Fluorescein Sodium
Water-soluble fluorescent dye that stains areas of corneal epithelial defects (ulcers, abrasions) green-yellow under cobalt blue light, enabling detection of corneal damage and assessment of tear film integrity
dogcat