Home/Medicines/Florfenicol
All medicines

Florfenicol

PrescriptionCDSCO approved
Amphenicol antibiotic (fluorinated chloramphenicol analogue)
Last reviewed 19 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
3 available
Formulations
2

Mechanism of action

Inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit; bacteriostatic; does not cause aplastic anaemia unlike chloramphenicol

At a glance

Class
Amphenicol antibiotic (fluorinated chloramphenicol analogue)
Schedule
Prescription
Storage
Store below 25°C, protect from light
CDSCO (India)
Vet-approved — 2000-01

Dosing

🐕

Dog

Susceptible bacterial infections (respiratory, soft tissue)
Dose
20–30 mg/kg
Route
PO, IM, SC
Frequency
BID
Max dose
1000 mg/dose; 2000 mg/day
Duration: 7–14 days
🐈

Cat

Susceptible bacterial infections
Dose
20–25 mg/kg
Route
PO, IM, SC
Frequency
BID
Max dose
250 mg/dose; 500 mg/day
Duration: 7–14 days
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💉

Injection — 1

Strength
300mg/mL
Available in India
🧴

Oral suspension — 1

Strength
25mg/mL

Storage

Store below 25°C, protect from light

Safety

Absolute contraindications — do not use

  • Known hypersensitivity to amphenicols

Use with caution

  • Breeding animals
    Reproductive safety not fully established in dogs/cats

Adverse effects

Common
Decreased appetite
Soft stools
Transient pain at injection site
Serious
Bone marrow suppression (reversible)
Optic neuritis (prolonged use)

Monitoring parameters

CBCClinical responseAppetite
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

No documented interactions.

Brands

International

Nuflor
Merck Animal Health

India

Floron
Intas
Vetflocin
Virbac India

FAQs

Frequently asked questions

What is Florfenicol?
Florfenicol is a amphenicol antibiotic (fluorinated chloramphenicol analogue) used in pets. Inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit; bacteriostatic; does not cause aplastic anaemia unlike chloramphenicol
What is Florfenicol used for in pets?
Florfenicol is used in veterinary medicine for: Susceptible bacterial infections (respiratory, soft tissue); Susceptible bacterial infections.
What is the Florfenicol dose for dogs?
For dogs, Florfenicol is typically dosed as follows — Susceptible bacterial infections (respiratory, soft tissue): 20–30 mg/kg PO/IM/SC BID. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Florfenicol dose for cats?
For cats, Florfenicol is typically dosed as follows — Susceptible bacterial infections: 20–25 mg/kg PO/IM/SC BID. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What are the side effects of Florfenicol?
Common: Decreased appetite, Soft stools, Transient pain at injection site. Serious (call your vet immediately): Bone marrow suppression (reversible), Optic neuritis (prolonged use).
Does Florfenicol need a prescription?
Yes. Florfenicol is a prescription medication and should only be administered under veterinary supervision.
When should Florfenicol not be used?
Do not use Florfenicol if: Known hypersensitivity to amphenicols.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database

Related medicines

Other medicines in the same class (Amphenicol antibiotic).

Chloramphenicol
Rx
Inhibits bacterial protein synthesis by binding reversibly to the 50S ribosomal subunit; bacteriostatic; broad-spectrum including anaerobes and intracellular organisms
dogcat
Need help? 💬
Chat with us on WhatsApp