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Filgrastim (G-CSF)

Prescription
Recombinant Granulocyte Colony-Stimulating Factor
Last reviewed 21 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
1 available
Formulations
1

Mechanism of action

Recombinant human G-CSF that stimulates proliferation, differentiation, and functional activation of neutrophil precursors in bone marrow. Increases circulating neutrophil count within 24h. Also mobilizes hematopoietic stem cells into peripheral blood.

At a glance

Class
Recombinant Granulocyte Colony-Stimulating Factor
Schedule
Prescription
Storage
Refrigerate 2–8°C; do not freeze or shake; stable at room temperature up to 24h

Dosing

🐕

Dog

Used for severe neutropenia (chemotherapy-induced, parvovirus, idiopathic)
Dose
5–10 mcg/kg
Route
SQ
Frequency
q24h
🐈

Cat

Same short-term limitations as dogs
Dose
5–10 mcg/kg
Route
SQ
Frequency
q24h
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Other — 1

Strength

Storage

Refrigerate 2–8°C; do not freeze or shake; stable at room temperature up to 24h

Safety

Monitoring parameters

CBC with differential daily during therapyStop when ANC >1000/µLMonitor for antibody formation (neutrophil count decline after initial response)
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

No documented interactions.

Brands

Other markets

Neupogen

FAQs

Frequently asked questions

What is Filgrastim (G-CSF)?
Filgrastim (G-CSF) is a recombinant granulocyte colony-stimulating factor used in pets. Recombinant human G-CSF that stimulates proliferation, differentiation, and functional activation of neutrophil precursors in bone marrow. Increases circulating neutrophil count within 24h. Also mobilizes hematopoietic stem cells into peripheral blood.
What is Filgrastim (G-CSF) used for in pets?
Filgrastim (G-CSF) is used in veterinary medicine for: Used for severe neutropenia (chemotherapy-induced, parvovirus, idiopathic); Same short-term limitations as dogs.
What is the Filgrastim (G-CSF) dose for dogs?
For dogs, Filgrastim (G-CSF) is typically dosed as follows — Used for severe neutropenia (chemotherapy-induced, parvovirus, idiopathic): 5–10 mcg/kg SQ q24h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Filgrastim (G-CSF) dose for cats?
For cats, Filgrastim (G-CSF) is typically dosed as follows — Same short-term limitations as dogs: 5–10 mcg/kg SQ q24h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
Does Filgrastim (G-CSF) need a prescription?
Yes. Filgrastim (G-CSF) is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database
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