Recombinant human G-CSF that stimulates proliferation, differentiation, and functional activation of neutrophil precursors in bone marrow. Increases circulating neutrophil count within 24h. Also mobilizes hematopoietic stem cells into peripheral blood.
At a glance
Class
Recombinant Granulocyte Colony-Stimulating Factor
Storage
Refrigerate 2–8°C; do not freeze or shake; stable at room temperature up to 24h
Dosing
Used for severe neutropenia (chemotherapy-induced, parvovirus, idiopathic)
Same short-term limitations as dogs
Safety
CBC with differential daily during therapyStop when ANC >1000/µLMonitor for antibody formation (neutrophil count decline after initial response)
Interactions
No documented interactions.
FAQs
Frequently asked questions
›What is Filgrastim (G-CSF)?
Filgrastim (G-CSF) is a recombinant granulocyte colony-stimulating factor used in pets. Recombinant human G-CSF that stimulates proliferation, differentiation, and functional activation of neutrophil precursors in bone marrow. Increases circulating neutrophil count within 24h. Also mobilizes hematopoietic stem cells into peripheral blood.
›What is Filgrastim (G-CSF) used for in pets?
Filgrastim (G-CSF) is used in veterinary medicine for: Used for severe neutropenia (chemotherapy-induced, parvovirus, idiopathic); Same short-term limitations as dogs.
›What is the Filgrastim (G-CSF) dose for dogs?
For dogs, Filgrastim (G-CSF) is typically dosed as follows — Used for severe neutropenia (chemotherapy-induced, parvovirus, idiopathic): 5–10 mcg/kg SQ q24h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Filgrastim (G-CSF) dose for cats?
For cats, Filgrastim (G-CSF) is typically dosed as follows — Same short-term limitations as dogs: 5–10 mcg/kg SQ q24h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›Does Filgrastim (G-CSF) need a prescription?
Yes. Filgrastim (G-CSF) is a prescription medication and should only be administered under veterinary supervision.
References
References
Textbooks & handbooks
- Plumb, D.C. Plumb's Veterinary Drug Handbook. 10th ed., Wiley-Blackwell, 2023.
- Vail, D.M., Thamm, D.H., & Liptak, J.M. (eds.). Withrow & MacEwen's Small Animal Clinical Oncology. 6th ed., Saunders/Elsevier, 2020.
- Riviere, J.E., & Papich, M.G. (eds.). Veterinary Pharmacology and Therapeutics. 10th ed., Wiley-Blackwell, 2018.
- National Research Council. Nutrient Requirements of Dogs and Cats. National Academies Press, Washington DC, 2006.
- The Merck Veterinary Manual. Merck & Co., Online edition. https://www.merckvetmanual.com/
Clinical guidelines & consensus
- Fletcher, D.J., Boller, M., Brainard, B.M., et al. "RECOVER Evidence and Knowledge Gap Analysis on Veterinary CPR." Journal of Veterinary Emergency and Critical Care, 2012;22(S1):S102–S131.
- American Animal Hospital Association. 2018 AAHA Diabetes Management Guidelines for Dogs and Cats. AAHA Press.
Journals & peer-reviewed studies
- Hogan, D.F., Fox, P.R., Jacob, K., et al. "Secondary prevention of cardiogenic arterial thromboembolism in the cat: The FAT CAT study." Journal of Veterinary Cardiology, 2015;17(Suppl 1):S306–S317.
- Boswood, A., Häggström, J., Gordon, S.G., et al. "Effect of Pimobendan in Dogs with Preclinical Myxomatous Mitral Valve Disease and Cardiomegaly: The EPIC Study — A Randomized Clinical Trial." Journal of Veterinary Internal Medicine, 2016;30(6):1765–1779.
- ASPCA Animal Poison Control Center. Toxicology and Poison Management Guidelines. American Society for the Prevention of Cruelty to Animals. https://www.aspca.org/pet-care/animal-poison-control
Regulatory & approvals
- Central Drugs Standard Control Organisation (CDSCO), Government of India. Veterinary Drug Approval Registry, 1969–2026. Directorate General of Health Services. https://cdsco.gov.in/
Databases
- Washington State University, College of Veterinary Medicine. Veterinary Clinical Pharmacology Laboratory (VCPL) — MDR1 Multidrug Sensitivity Database. https://vcpl.vetmed.wsu.edu/
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
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