Non-sedating selective H1-receptor antagonist that does not cross the blood-brain barrier significantly. No anticholinergic activity. No cardiac QT prolongation.
At a glance
Class
Second-Generation Antihistamine (Non-Sedating H1 Blocker)
Storage
Store at room temperature below 25°C, protect from moisture
Dosing
Non-sedating alternative for allergic dermatitis and urticaria
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Safety
Pruritus/allergy response
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Interactions
No documented interactions.
FAQs
Frequently asked questions
›What is Fexofenadine?
Fexofenadine is a second-generation antihistamine (non-sedating h1 blocker) used in pets. Non-sedating selective H1-receptor antagonist that does not cross the blood-brain barrier significantly. No anticholinergic activity. No cardiac QT prolongation.
›What is Fexofenadine used for in pets?
Fexofenadine is used in veterinary medicine for: Non-sedating alternative for allergic dermatitis and urticaria; Non-sedating.
›What is the Fexofenadine dose for dogs?
For dogs, Fexofenadine is typically dosed as follows — Non-sedating alternative for allergic dermatitis and urticaria: 2–5 mg/kg PO q12–24h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Fexofenadine dose for cats?
For cats, Fexofenadine is typically dosed as follows — Non-sedating: undefined undefined PO q12h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›Does Fexofenadine need a prescription?
Fexofenadine is available over the counter. Even so, you should consult your veterinarian before giving any medication to your pet.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →References
References
The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.
Textbooks & handbooks — 5
- Plumb's Veterinary Drug Handbook
- Withrow & MacEwen's Small Animal Clinical Oncology
- Merck Veterinary Manual
- NRC Nutrient Requirements of Dogs and Cats
- Veterinary Pharmacology and Therapeutics (Riviere & Papich)
Clinical guidelines & consensus — 4
- ASPCA Animal Poison Control Center Guidelines
- AAHA Diabetes Management Guidelines
- ASPCA Poison Control Guidelines
- RECOVER CPR Guidelines
Journals & peer-reviewed studies — 2
- EPIC Study (J Vet Intern Med 2016)
- JVIM FAT CAT Study
Regulatory & approvals — 1
- CDSCO Veterinary Drug Approval Registry (1969–2026)
Databases — 1
- Washington State University VCPL MDR1 Database