Selective dopamine D1 receptor agonist that causes renal and mesenteric vasodilation, increases renal blood flow, glomerular filtration rate, and sodium excretion without activating D2 receptors (no nausea). Used for acute hypertensive crises.
At a glance
Class
Selective Dopamine D1 Receptor Agonist / Antihypertensive
Storage
Store at room temperature; diluted solution stable 24h at room temperature
Dosing
Used for acute hypertensive emergencies, oliguric acute kidney injury (increases
Frequency
Continuous infusion
Used for acute hypertension and AKI
Safety
Blood pressure q5–15 min during titrationHeart rateUrine outputSerum potassiumIOP if glaucoma risk
Interactions
No documented interactions.
FAQs
Frequently asked questions
›What is Fenoldopam?
Fenoldopam is a selective dopamine d1 receptor agonist / antihypertensive used in pets. Selective dopamine D1 receptor agonist that causes renal and mesenteric vasodilation, increases renal blood flow, glomerular filtration rate, and sodium excretion without activating D2 receptors (no nausea). Used for acute hypertensive crises.
›What is Fenoldopam used for in pets?
Fenoldopam is used in veterinary medicine for: Used for acute hypertensive emergencies, oliguric acute kidney injury (increases; Used for acute hypertension and AKI.
›What is the Fenoldopam dose for dogs?
For dogs, Fenoldopam is typically dosed as follows — Used for acute hypertensive emergencies, oliguric acute kidney injury (increases: 0.1–0.8 mcg/kg IV CRI Continuous infusion. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Fenoldopam dose for cats?
For cats, Fenoldopam is typically dosed as follows — Used for acute hypertension and AKI: 0.1–0.5 mcg/kg IV CRI Continuous. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›Does Fenoldopam need a prescription?
Yes. Fenoldopam is a prescription medication and should only be administered under veterinary supervision.
References
References
Textbooks & handbooks
- Plumb, D.C. Plumb's Veterinary Drug Handbook. 10th ed., Wiley-Blackwell, 2023.
- Vail, D.M., Thamm, D.H., & Liptak, J.M. (eds.). Withrow & MacEwen's Small Animal Clinical Oncology. 6th ed., Saunders/Elsevier, 2020.
- Riviere, J.E., & Papich, M.G. (eds.). Veterinary Pharmacology and Therapeutics. 10th ed., Wiley-Blackwell, 2018.
- National Research Council. Nutrient Requirements of Dogs and Cats. National Academies Press, Washington DC, 2006.
- The Merck Veterinary Manual. Merck & Co., Online edition. https://www.merckvetmanual.com/
Clinical guidelines & consensus
- Fletcher, D.J., Boller, M., Brainard, B.M., et al. "RECOVER Evidence and Knowledge Gap Analysis on Veterinary CPR." Journal of Veterinary Emergency and Critical Care, 2012;22(S1):S102–S131.
- American Animal Hospital Association. 2018 AAHA Diabetes Management Guidelines for Dogs and Cats. AAHA Press.
Journals & peer-reviewed studies
- Hogan, D.F., Fox, P.R., Jacob, K., et al. "Secondary prevention of cardiogenic arterial thromboembolism in the cat: The FAT CAT study." Journal of Veterinary Cardiology, 2015;17(Suppl 1):S306–S317.
- Boswood, A., Häggström, J., Gordon, S.G., et al. "Effect of Pimobendan in Dogs with Preclinical Myxomatous Mitral Valve Disease and Cardiomegaly: The EPIC Study — A Randomized Clinical Trial." Journal of Veterinary Internal Medicine, 2016;30(6):1765–1779.
- ASPCA Animal Poison Control Center. Toxicology and Poison Management Guidelines. American Society for the Prevention of Cruelty to Animals. https://www.aspca.org/pet-care/animal-poison-control
Regulatory & approvals
- Central Drugs Standard Control Organisation (CDSCO), Government of India. Veterinary Drug Approval Registry, 1969–2026. Directorate General of Health Services. https://cdsco.gov.in/
Databases
- Washington State University, College of Veterinary Medicine. Veterinary Clinical Pharmacology Laboratory (VCPL) — MDR1 Multidrug Sensitivity Database. https://vcpl.vetmed.wsu.edu/
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
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