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Felbamate

Prescription
Anticonvulsant (Dicarbamate)
Last reviewed 21 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
1 available
Formulations
2

Mechanism of action

Blocks NMDA receptors (glycine binding site), inhibits voltage-gated sodium channels, and potentiates GABA-A receptor function. Unique triple mechanism provides broad-spectrum anticonvulsant activity for refractory epilepsy.

At a glance

Class
Anticonvulsant (Dicarbamate)
Schedule
Prescription
Storage
Store at room temperature below 30°C

Dosing

🐕

Dog

Reserved for refractory canine epilepsy unresponsive to phenobarbital, potassium
Dose
15–65 mg/kg
Route
PO
Frequency
q8h
🐈

Cat

Insufficient feline safety/efficacy data
Dose
Route
PO
Frequency
N/A
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Other — 2

Strength
Strength

Storage

Store at room temperature below 30°C

Safety

Monitoring parameters

CBC every 2 weeks for first 6 months then monthlyHepatic enzymesSeizure diarySchirmer tear test (KCS)
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

No documented interactions.

Brands

Other markets

Felbatol

FAQs

Frequently asked questions

What is Felbamate?
Felbamate is a anticonvulsant (dicarbamate) used in pets. Blocks NMDA receptors (glycine binding site), inhibits voltage-gated sodium channels, and potentiates GABA-A receptor function. Unique triple mechanism provides broad-spectrum anticonvulsant activity for refractory epilepsy.
What is Felbamate used for in pets?
Felbamate is used in veterinary medicine for: Reserved for refractory canine epilepsy unresponsive to phenobarbital, potassium; Insufficient feline safety/efficacy data.
What is the Felbamate dose for dogs?
For dogs, Felbamate is typically dosed as follows — Reserved for refractory canine epilepsy unresponsive to phenobarbital, potassium: 15–65 mg/kg PO q8h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Felbamate dose for cats?
For cats, Felbamate is typically dosed as follows — Insufficient feline safety/efficacy data: undefined undefined PO N/A. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
Does Felbamate need a prescription?
Yes. Felbamate is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database

Related medicines

Other medicines in the same class (Anticonvulsant).

Topiramate
Rx
Multiple mechanisms: blocks voltage-gated sodium channels, enhances GABA-A receptor activity, inhibits AMPA/kainate glutamate receptors, and weakly inhibits carbonic anhydrase. Broad-spectrum anticonvulsant for refractory epilepsy.
dogcat
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