Inhibits arabinosyl transferase (embB gene product), blocking arabinogalactan synthesis in the mycobacterial cell wall. Bacteriostatic. Used in combination therapy to prevent resistance development of rifampicin and isoniazid.
At a glance
Class
Antimycobacterial Agent
Storage
Store at room temperature below 30°C, protect from moisture
Dosing
Used for Mycobacterium tuberculosis complex and M
Used for feline mycobacterial infections (M
Safety
Visual assessment (difficult in animals — fundic exam)Renal function (dose adjustment)Hepatic enzymesClinical/culture response
Interactions
No documented interactions.
FAQs
Frequently asked questions
›What is Ethambutol?
Ethambutol is a antimycobacterial agent used in pets. Inhibits arabinosyl transferase (embB gene product), blocking arabinogalactan synthesis in the mycobacterial cell wall. Bacteriostatic. Used in combination therapy to prevent resistance development of rifampicin and isoniazid.
›What is Ethambutol used for in pets?
Ethambutol is used in veterinary medicine for: Used for Mycobacterium tuberculosis complex and M; Used for feline mycobacterial infections (M.
›What is the Ethambutol dose for dogs?
For dogs, Ethambutol is typically dosed as follows — Used for Mycobacterium tuberculosis complex and M: 15 mg/kg PO q24h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Ethambutol dose for cats?
For cats, Ethambutol is typically dosed as follows — Used for feline mycobacterial infections (M: 15 mg/kg PO q24h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›Does Ethambutol need a prescription?
Yes. Ethambutol is a prescription medication and should only be administered under veterinary supervision.
References
References
Textbooks & handbooks
- Plumb, D.C. Plumb's Veterinary Drug Handbook. 10th ed., Wiley-Blackwell, 2023.
- Vail, D.M., Thamm, D.H., & Liptak, J.M. (eds.). Withrow & MacEwen's Small Animal Clinical Oncology. 6th ed., Saunders/Elsevier, 2020.
- Riviere, J.E., & Papich, M.G. (eds.). Veterinary Pharmacology and Therapeutics. 10th ed., Wiley-Blackwell, 2018.
- National Research Council. Nutrient Requirements of Dogs and Cats. National Academies Press, Washington DC, 2006.
- The Merck Veterinary Manual. Merck & Co., Online edition. https://www.merckvetmanual.com/
Clinical guidelines & consensus
- Fletcher, D.J., Boller, M., Brainard, B.M., et al. "RECOVER Evidence and Knowledge Gap Analysis on Veterinary CPR." Journal of Veterinary Emergency and Critical Care, 2012;22(S1):S102–S131.
- American Animal Hospital Association. 2018 AAHA Diabetes Management Guidelines for Dogs and Cats. AAHA Press.
Journals & peer-reviewed studies
- Hogan, D.F., Fox, P.R., Jacob, K., et al. "Secondary prevention of cardiogenic arterial thromboembolism in the cat: The FAT CAT study." Journal of Veterinary Cardiology, 2015;17(Suppl 1):S306–S317.
- Boswood, A., Häggström, J., Gordon, S.G., et al. "Effect of Pimobendan in Dogs with Preclinical Myxomatous Mitral Valve Disease and Cardiomegaly: The EPIC Study — A Randomized Clinical Trial." Journal of Veterinary Internal Medicine, 2016;30(6):1765–1779.
- ASPCA Animal Poison Control Center. Toxicology and Poison Management Guidelines. American Society for the Prevention of Cruelty to Animals. https://www.aspca.org/pet-care/animal-poison-control
Regulatory & approvals
- Central Drugs Standard Control Organisation (CDSCO), Government of India. Veterinary Drug Approval Registry, 1969–2026. Directorate General of Health Services. https://cdsco.gov.in/
Databases
- Washington State University, College of Veterinary Medicine. Veterinary Clinical Pharmacology Laboratory (VCPL) — MDR1 Multidrug Sensitivity Database. https://vcpl.vetmed.wsu.edu/
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →