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Dorzolamide Ophthalmic

Prescription
Ophthalmic Carbonic Anhydrase Inhibitor
Last reviewed 22 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
2 available
Formulations
2

Mechanism of action

Topical carbonic anhydrase II inhibitor that reduces aqueous humor production by the ciliary body. Lowers IOP without affecting pupil size or accommodation. Often combined with timolol (Cosopt) for additive effect.

At a glance

Class
Ophthalmic Carbonic Anhydrase Inhibitor
Schedule
Prescription
Storage
Store at room temperature; discard 28 days after opening

Dosing

🐕

Dog

First-line chronic glaucoma therapy
Dose
Route
Ophthalmic
Frequency
q8–12h
🐈

Cat

Used for feline glaucoma
Dose
Route
Ophthalmic
Frequency
q8–12h
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Other — 2

Strength
Strength

Storage

Store at room temperature; discard 28 days after opening

Safety

Monitoring parameters

IOP measurement q2–4 weeks initiallyOcular surface toleranceHeart rate (Cosopt — timolol)
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

No documented interactions.

Brands

Other markets

Trusopt
Merck
Cosopt (with timolol)
Merck

FAQs

Frequently asked questions

What is Dorzolamide Ophthalmic?
Dorzolamide Ophthalmic is a ophthalmic carbonic anhydrase inhibitor used in pets. Topical carbonic anhydrase II inhibitor that reduces aqueous humor production by the ciliary body. Lowers IOP without affecting pupil size or accommodation. Often combined with timolol (Cosopt) for additive effect.
What is Dorzolamide Ophthalmic used for in pets?
Dorzolamide Ophthalmic is used in veterinary medicine for: First-line chronic glaucoma therapy; Used for feline glaucoma.
What is the Dorzolamide Ophthalmic dose for dogs?
For dogs, Dorzolamide Ophthalmic is typically dosed as follows — First-line chronic glaucoma therapy: undefined undefined Ophthalmic q8–12h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Dorzolamide Ophthalmic dose for cats?
For cats, Dorzolamide Ophthalmic is typically dosed as follows — Used for feline glaucoma: undefined undefined Ophthalmic q8–12h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
Does Dorzolamide Ophthalmic need a prescription?
Yes. Dorzolamide Ophthalmic is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database

Related medicines

Other medicines in the same class (Ophthalmic Carbonic Anhydrase Inhibitor).

Brinzolamide Ophthalmic
Rx
Topical carbonic anhydrase II inhibitor that reduces aqueous humor production in the ciliary body, lowering IOP. Unlike systemic CAIs (acetazolamide), topical brinzolamide has minimal systemic side effects.
dogcat
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