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Dopamine

Prescription
Sympathomimetic / Vasopressor / Inotrope
Last reviewed 21 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
1 available
Interactions
2 documented
Formulations
1

Mechanism of action

Dose-dependent receptor effects: Low (1–3 mcg/kg/min) = dopaminergic (renal vasodilation); Medium (3–10) = beta-1 (positive inotropy); High (>10) = alpha-1 (vasoconstriction).

At a glance

Class
Sympathomimetic / Vasopressor / Inotrope
Schedule
Prescription
Storage
Store at room temperature; protect from light; discard if discolored

Dosing

🐕

Dog

Used for cardiogenic shock, oliguric renal failure, refractory hypotension
Dose
1–3 mcg/kg
Route
IV CRI only
Frequency
Continuous
🐈

Cat

Cats may be more susceptible to arrhythmias
Dose
2–10 mcg/kg
Route
IV CRI
Frequency
Continuous
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Other — 1

Strength

Storage

Store at room temperature; protect from light; discard if discolored

Safety

Monitoring parameters

Continuous ECGBlood pressureUrine outputLactateIV site integrity
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

Major — 1

Propranolol
major
Beta-blockers antagonize dopamine's beta-1 cardiac stimulatory effects (inotropy, chronotropy), leaving only alpha-mediated vasoconstriction at higher doses.
Management: If vasopressor needed in patient on beta-blocker, consider norepinephrine or phenylephrine (pure alpha) instead of dopamine. Higher dopamine doses may worsen hypertension without improving cardiac output.

Moderate — 1

Phenobarbital
moderate
Phenobarbital may reduce dopamine's hemodynamic effects through CNS depression and altered autonomic reflexes.
Management: May need higher dopamine infusion rates. Titrate to effect using blood pressure and urine output as endpoints.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Brands

Other markets

Intropin

FAQs

Frequently asked questions

What is Dopamine?
Dopamine is a sympathomimetic / vasopressor / inotrope used in pets. Dose-dependent receptor effects: Low (1–3 mcg/kg/min) = dopaminergic (renal vasodilation); Medium (3–10) = beta-1 (positive inotropy); High (>10) = alpha-1 (vasoconstriction).
What is Dopamine used for in pets?
Dopamine is used in veterinary medicine for: Used for cardiogenic shock, oliguric renal failure, refractory hypotension; Cats may be more susceptible to arrhythmias.
What is the Dopamine dose for dogs?
For dogs, Dopamine is typically dosed as follows — Used for cardiogenic shock, oliguric renal failure, refractory hypotension: 1–3 mcg/kg IV CRI only Continuous. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Dopamine dose for cats?
For cats, Dopamine is typically dosed as follows — Cats may be more susceptible to arrhythmias: 2–10 mcg/kg IV CRI Continuous. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
Does Dopamine need a prescription?
Yes. Dopamine is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database
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