Natural prostaglandin F2α that causes luteolysis (corpus luteum regression) by decreasing progesterone production, smooth muscle contraction of the uterus and GI tract, and bronchoconstriction. Used for estrus induction and pyometra treatment.
At a glance
Class
Prostaglandin F2α (PGF2α)
Storage
Store at 2–25°C, protect from light
Dosing
Low-dose protocol preferred to minimize side effects
Frequency
q12–24h (pyometra) or once (luteolysis)
Cats are more sensitive to PGF2α side effects — vocalization, salivation, and GI
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Safety
Vaginal discharge characterSerial ultrasound to monitor uterine sizeCBC and biochemistry (systemic response in pyometra)Temperature
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Interactions
No documented interactions.
FAQs
Frequently asked questions
›What is Dinoprost?
Dinoprost is a prostaglandin f2α (pgf2α) used in pets. Natural prostaglandin F2α that causes luteolysis (corpus luteum regression) by decreasing progesterone production, smooth muscle contraction of the uterus and GI tract, and bronchoconstriction. Used for estrus induction and pyometra treatment.
›What is Dinoprost used for in pets?
Dinoprost is used in veterinary medicine for: Low-dose protocol preferred to minimize side effects; Cats are more sensitive to PGF2α side effects — vocalization, salivation, and GI.
›What is the Dinoprost dose for dogs?
For dogs, Dinoprost is typically dosed as follows — Low-dose protocol preferred to minimize side effects: 25–100 mcg/kg SQ q12–24h (pyometra) or once (luteolysis). Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Dinoprost dose for cats?
For cats, Dinoprost is typically dosed as follows — Cats are more sensitive to PGF2α side effects — vocalization, salivation, and GI: 100 mcg/kg SQ q12–24h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›Does Dinoprost need a prescription?
Yes. Dinoprost is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →References
CDSCO approvals (India) — 1
SND Dinoprost Tromethamine Injection 12.5 mg/ml
M/s Zoetis India Limited, 31, 3rd Floor, Kalpataru Synergy, · Approved 12.03.2026
1. For estrus synchronization in beef cows, beef heifers and replacement dairy heifers. 2. For unobserved (silent) estru
Source: CDSCO Veterinary Drug Approval Registry (1969–2026)
References
The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.
Textbooks & handbooks — 5
- Plumb's Veterinary Drug Handbook
- Withrow & MacEwen's Small Animal Clinical Oncology
- Merck Veterinary Manual
- NRC Nutrient Requirements of Dogs and Cats
- Veterinary Pharmacology and Therapeutics (Riviere & Papich)
Clinical guidelines & consensus — 4
- ASPCA Animal Poison Control Center Guidelines
- AAHA Diabetes Management Guidelines
- ASPCA Poison Control Guidelines
- RECOVER CPR Guidelines
Journals & peer-reviewed studies — 2
- EPIC Study (J Vet Intern Med 2016)
- JVIM FAT CAT Study
Regulatory & approvals — 1
- CDSCO Veterinary Drug Approval Registry (1969–2026)
Databases — 1
- Washington State University VCPL MDR1 Database