Home/Medicines/Diazoxide
All medicines

Diazoxide

Prescription
Benzothiadiazine / Hyperglycemic Agent
Last reviewed 21 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
1 available
Formulations
2

Mechanism of action

Opens ATP-sensitive potassium channels in pancreatic beta cells, inhibiting insulin secretion. Also reduces peripheral glucose utilization. Used for insulinoma-associated hypoglycemia.

At a glance

Class
Benzothiadiazine / Hyperglycemic Agent
Schedule
Prescription
Storage
Store at room temperature; protect from light

Dosing

🐕

Dog

Primary medical management for insulinoma-associated hypoglycemia
Dose
5–30 mg/kg
Route
PO
Frequency
q12h
🐈

Cat

Feline insulinoma is uncommon
Dose
5 mg/kg
Route
PO
Frequency
q12h
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Other — 2

Strength
Strength

Storage

Store at room temperature; protect from light

Safety

Monitoring parameters

Blood glucose curvesBody weightCataract developmentGI tolerance
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

No documented interactions.

Brands

Other markets

Proglycem

FAQs

Frequently asked questions

What is Diazoxide?
Diazoxide is a benzothiadiazine / hyperglycemic agent used in pets. Opens ATP-sensitive potassium channels in pancreatic beta cells, inhibiting insulin secretion. Also reduces peripheral glucose utilization. Used for insulinoma-associated hypoglycemia.
What is Diazoxide used for in pets?
Diazoxide is used in veterinary medicine for: Primary medical management for insulinoma-associated hypoglycemia; Feline insulinoma is uncommon.
What is the Diazoxide dose for dogs?
For dogs, Diazoxide is typically dosed as follows — Primary medical management for insulinoma-associated hypoglycemia: 5–30 mg/kg PO q12h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Diazoxide dose for cats?
For cats, Diazoxide is typically dosed as follows — Feline insulinoma is uncommon: 5 mg/kg PO q12h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
Does Diazoxide need a prescription?
Yes. Diazoxide is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database
Need help? 💬
Chat with us on WhatsApp