Intracellularly converted to an iron chelator that prevents iron-catalyzed free radical generation responsible for anthracycline cardiotoxicity. Does not reduce antitumor efficacy.
At a glance
Class
Cardioprotective Agent / Iron Chelator
Storage
Store at room temperature; reconstituted use within 1h; diluted within 6h
Dosing
Allows higher cumulative doxorubicin doses by protecting against cardiotoxicity
Frequency
With each doxorubicin treatment
Limited feline data but same rationale
Frequency
With each doxorubicin dose
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Safety
CBCEchocardiogram (continued monitoring)Tumor response
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Interactions
No documented interactions.
FAQs
Frequently asked questions
›What is Dexrazoxane?
Dexrazoxane is a cardioprotective agent / iron chelator used in pets. Intracellularly converted to an iron chelator that prevents iron-catalyzed free radical generation responsible for anthracycline cardiotoxicity. Does not reduce antitumor efficacy.
›What is Dexrazoxane used for in pets?
Dexrazoxane is used in veterinary medicine for: Allows higher cumulative doxorubicin doses by protecting against cardiotoxicity; Limited feline data but same rationale.
›What is the Dexrazoxane dose for dogs?
For dogs, Dexrazoxane is typically dosed as follows — Allows higher cumulative doxorubicin doses by protecting against cardiotoxicity: undefined undefined PO With each doxorubicin treatment. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Dexrazoxane dose for cats?
For cats, Dexrazoxane is typically dosed as follows — Limited feline data but same rationale: undefined undefined IV With each doxorubicin dose. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›Does Dexrazoxane need a prescription?
Yes. Dexrazoxane is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →References
References
The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.
Textbooks & handbooks — 5
- Plumb's Veterinary Drug Handbook
- Withrow & MacEwen's Small Animal Clinical Oncology
- Merck Veterinary Manual
- NRC Nutrient Requirements of Dogs and Cats
- Veterinary Pharmacology and Therapeutics (Riviere & Papich)
Clinical guidelines & consensus — 4
- ASPCA Animal Poison Control Center Guidelines
- AAHA Diabetes Management Guidelines
- ASPCA Poison Control Guidelines
- RECOVER CPR Guidelines
Journals & peer-reviewed studies — 2
- EPIC Study (J Vet Intern Med 2016)
- JVIM FAT CAT Study
Regulatory & approvals — 1
- CDSCO Veterinary Drug Approval Registry (1969–2026)
Databases — 1
- Washington State University VCPL MDR1 Database