Home/Medicines/Desflurane
All medicines

Desflurane

Prescription
Halogenated Inhalant Anesthetic
Last reviewed 21 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
1 available
Formulations
1

Mechanism of action

Volatile fluorinated methyl ethyl ether with the lowest blood:gas solubility coefficient of all clinical inhalants (0.42), allowing the fastest induction, depth adjustment, and recovery. Requires heated vaporizer (boiling point 23.5°C).

At a glance

Class
Halogenated Inhalant Anesthetic
Schedule
Prescription
Storage
Store at room temperature; keep below 23.5°C to prevent boiling outside vaporizer

Dosing

🐕

Dog

Fastest recovery of all inhalants
Dose
Route
Inhalation
Frequency
Continuous during anesthesia
🐈

Cat

Very pungent — mask induction contraindicated (laryngospasm)
Dose
Route
Inhalation
Frequency
Continuous
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Other — 1

Strength

Storage

Store at room temperature; keep below 23.5°C to prevent boiling outside vaporizer

Safety

Monitoring parameters

SpO2ETCO2Blood pressureECGTemperatureAnesthetic depth
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

No documented interactions.

Brands

Other markets

Suprane

FAQs

Frequently asked questions

What is Desflurane?
Desflurane is a halogenated inhalant anesthetic used in pets. Volatile fluorinated methyl ethyl ether with the lowest blood:gas solubility coefficient of all clinical inhalants (0.42), allowing the fastest induction, depth adjustment, and recovery. Requires heated vaporizer (boiling point 23.5°C).
What is Desflurane used for in pets?
Desflurane is used in veterinary medicine for: Fastest recovery of all inhalants; Very pungent — mask induction contraindicated (laryngospasm).
What is the Desflurane dose for dogs?
For dogs, Desflurane is typically dosed as follows — Fastest recovery of all inhalants: undefined undefined Inhalation Continuous during anesthesia. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Desflurane dose for cats?
For cats, Desflurane is typically dosed as follows — Very pungent — mask induction contraindicated (laryngospasm): undefined undefined Inhalation Continuous. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
Does Desflurane need a prescription?
Yes. Desflurane is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database

Related medicines

Other medicines in the same class (Halogenated Inhalant Anesthetic).

Sevoflurane
Rx
Fluorinated methyl isopropyl ether with lower blood:gas solubility than isoflurane (0.65 vs 1.4), allowing faster induction, more precise adjustment of anesthetic depth, and significantly faster recovery. Similar GABA/NMDA mechanism to isoflurane.
dogcat
Need help? 💬
Chat with us on WhatsApp