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Deferoxamine

Prescription
Iron Chelating Agent
Last reviewed 21 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
1 available
Formulations
1

Mechanism of action

Hexadentate chelator with high affinity and specificity for ferric iron (Fe3+), forming ferrioxamine complex that is excreted renally. Does not significantly chelate essential trace metals (calcium, zinc, copper) at therapeutic doses.

At a glance

Class
Iron Chelating Agent
Schedule
Prescription
Storage
Powder at room temperature below 25°C; reconstituted solution use within 24h at room temperature

Dosing

🐕

Dog

Treatment for acute iron toxicity (iron supplementation overdose, iron-containin
Dose
10–15 mg/kg
Route
IV (CRI preferred), IM, SQ
Frequency
Continuous IV or q4–8h IM/SQ
🐈

Cat

Iron toxicity less common in cats
Dose
40 mg/kg
Route
IM
Frequency
q4h
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Other — 1

Strength

Storage

Powder at room temperature below 25°C; reconstituted solution use within 24h at room temperature

Safety

Monitoring parameters

Serum iron levels before and during treatmentUrine color (vin rosé = active chelation)Blood pressure (IV infusion)Renal function
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

No documented interactions.

Brands

Other markets

Desferal

FAQs

Frequently asked questions

What is Deferoxamine?
Deferoxamine is a iron chelating agent used in pets. Hexadentate chelator with high affinity and specificity for ferric iron (Fe3+), forming ferrioxamine complex that is excreted renally. Does not significantly chelate essential trace metals (calcium, zinc, copper) at therapeutic doses.
What is Deferoxamine used for in pets?
Deferoxamine is used in veterinary medicine for: Treatment for acute iron toxicity (iron supplementation overdose, iron-containin; Iron toxicity less common in cats.
What is the Deferoxamine dose for dogs?
For dogs, Deferoxamine is typically dosed as follows — Treatment for acute iron toxicity (iron supplementation overdose, iron-containin: 10–15 mg/kg IV (CRI preferred)/IM/SQ Continuous IV or q4–8h IM/SQ. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Deferoxamine dose for cats?
For cats, Deferoxamine is typically dosed as follows — Iron toxicity less common in cats: 40 mg/kg IM q4h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
Does Deferoxamine need a prescription?
Yes. Deferoxamine is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database
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