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Cyclopentolate Ophthalmic

Prescription
Ophthalmic Anticholinergic / Short-Acting Cycloplegic
Last reviewed 22 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
1 available
Formulations
1

Mechanism of action

Muscarinic receptor antagonist causing mydriasis and cycloplegia. Shorter duration than atropine (24h vs 7–14 days in dogs), making it more suitable for diagnostic fundoscopy when prolonged mydriasis is undesirable.

At a glance

Class
Ophthalmic Anticholinergic / Short-Acting Cycloplegic
Schedule
Prescription
Storage
Store at room temperature, protect from light

Dosing

🐕

Dog

Preferred over atropine for diagnostic mydriasis (shorter duration — 24h vs 7–14
Dose
Route
Ophthalmic
Frequency
Once for diagnostic; q8–12h for short-term cycloplegia
🐈

Cat

Cats respond well
Dose
Route
Ophthalmic
Frequency
Once for diagnostic
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Other — 1

Strength

Storage

Store at room temperature, protect from light

Safety

Monitoring parameters

Pupil dilation responseIOP (if glaucoma risk)
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

No documented interactions.

Brands

Other markets

Cyclogyl
Alcon

FAQs

Frequently asked questions

What is Cyclopentolate Ophthalmic?
Cyclopentolate Ophthalmic is a ophthalmic anticholinergic / short-acting cycloplegic used in pets. Muscarinic receptor antagonist causing mydriasis and cycloplegia. Shorter duration than atropine (24h vs 7–14 days in dogs), making it more suitable for diagnostic fundoscopy when prolonged mydriasis is undesirable.
What is Cyclopentolate Ophthalmic used for in pets?
Cyclopentolate Ophthalmic is used in veterinary medicine for: Preferred over atropine for diagnostic mydriasis (shorter duration — 24h vs 7–14; Cats respond well.
What is the Cyclopentolate Ophthalmic dose for dogs?
For dogs, Cyclopentolate Ophthalmic is typically dosed as follows — Preferred over atropine for diagnostic mydriasis (shorter duration — 24h vs 7–14: undefined undefined Ophthalmic Once for diagnostic; q8–12h for short-term cycloplegia. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Cyclopentolate Ophthalmic dose for cats?
For cats, Cyclopentolate Ophthalmic is typically dosed as follows — Cats respond well: undefined undefined Ophthalmic Once for diagnostic. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
Does Cyclopentolate Ophthalmic need a prescription?
Yes. Cyclopentolate Ophthalmic is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database
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