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Clonazepam

Benzodiazepine Anticonvulsant / Anxiolytic

Last reviewed 21 Apr 2026 · PetCare.AI Editorial Team

Species

Dog, Cat

Brands

2 available

Interactions

1 documented

Formulations

Mechanism of action

Enhances GABA-A receptor function by binding the benzodiazepine allosteric site, increasing chloride channel opening. Potent anticonvulsant with longer duration than diazepam.

At a glance

Class

Benzodiazepine Anticonvulsant / Anxiolytic

Schedule

Controlled Substance

Storage

Store at room temperature, protect from light and moisture

Dosing

🐕

Dog

Adjunct anticonvulsant and anxiolytic

Dose

0.1–1 mg/kg

Route

Frequency

q8–12h

🐈

Cat

Used for feline anxiety and adjunct seizure management

Dose

0.1–0.2 mg/kg

Route

Frequency

q12–24h

Educational reference only

This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Other — 2

Strength

—

Strength

—

Storage

Store at room temperature, protect from light and moisture

Safety

Monitoring parameters

Seizure diaryHepatic enzymes (especially cats)Sedation levelBody weight

Educational reference only

Interactions

Moderate — 1

Phenobarbital

moderate

Additive CNS depression. Phenobarbital induces CYP enzymes metabolizing clonazepam, potentially reducing clonazepam levels.

Management: Standard adjunct anticonvulsant combination. May need higher clonazepam dose with phenobarbital. Monitor sedation.

Educational reference only

Brands

Other markets

Klonopin

Rivotril

FAQs

Frequently asked questions

›What is Clonazepam?

Clonazepam is a benzodiazepine anticonvulsant / anxiolytic used in pets. Enhances GABA-A receptor function by binding the benzodiazepine allosteric site, increasing chloride channel opening. Potent anticonvulsant with longer duration than diazepam.

›What is Clonazepam used for in pets?

Clonazepam is used in veterinary medicine for: Adjunct anticonvulsant and anxiolytic; Used for feline anxiety and adjunct seizure management.

›What is the Clonazepam dose for dogs?

For dogs, Clonazepam is typically dosed as follows — Adjunct anticonvulsant and anxiolytic: 0.1–1 mg/kg PO q8–12h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.

›What is the Clonazepam dose for cats?

For cats, Clonazepam is typically dosed as follows — Used for feline anxiety and adjunct seizure management: 0.1–0.2 mg/kg PO q12–24h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.

›Does Clonazepam need a prescription?

Clonazepam is available over the counter. Even so, you should consult your veterinarian before giving any medication to your pet.

Educational reference only