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Carboplatin

Prescription

Platinum-Based Chemotherapy

Last reviewed 21 Apr 2026 · PetCare.AI Editorial Team

Species

Dog, Cat

Brands

2 available

Interactions

2 documented

Formulations

Mechanism of action

Alkylating-like platinum complex that forms intrastrand and interstrand DNA crosslinks, preventing DNA replication and transcription. Less nephrotoxic than cisplatin but more myelosuppressive. Safe for use in cats.

At a glance

Class

Platinum-Based Chemotherapy

Schedule

Prescription (Chemotherapy)

Storage

Store at room temperature; protect from light; do not refrigerate (precipitates); do not use aluminum needles

Dosing

🐕

Dog

Used for osteosarcoma, transitional cell carcinoma, nasal tumors, and carcinomas

Dose

300 mg/m²

Route

Frequency

q3–4 weeks

🐈

Cat

Safe in cats — unlike cisplatin

Dose

200–240 mg/m²

Route

Frequency

q3–4 weeks

Educational reference only

This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Other — 1

Strength

—

Storage

Store at room temperature; protect from light; do not refrigerate (precipitates); do not use aluminum needles

Safety

Monitoring parameters

CBC at nadir before each cycleRenal function (creatinine, BUN, urinalysis)Serum electrolytes

Educational reference only

Interactions

Major — 1

Gentamicin (Systemic)

major

Both nephrotoxic: carboplatin (less than cisplatin but still significant at cumulative doses) + gentamicin (proximal tubular). Additive renal injury risk.

Management: Avoid concurrent use. If both needed, allow renal recovery between agents. Monitor BUN/creatinine closely.

Moderate — 1

Meloxicam

moderate

NSAID prostaglandin inhibition reduces renal blood flow, potentially worsening carboplatin renal effects.

Management: Use cautiously. Ensure adequate hydration. Monitor renal function.

Educational reference only

Brands

Other markets

Paraplatin

Carboplat

FAQs

Frequently asked questions

›What is Carboplatin?

Carboplatin is a platinum-based chemotherapy used in pets. Alkylating-like platinum complex that forms intrastrand and interstrand DNA crosslinks, preventing DNA replication and transcription. Less nephrotoxic than cisplatin but more myelosuppressive. Safe for use in cats.

›What is Carboplatin used for in pets?

Carboplatin is used in veterinary medicine for: Used for osteosarcoma, transitional cell carcinoma, nasal tumors, and carcinomas; Safe in cats — unlike cisplatin.

›What is the Carboplatin dose for dogs?

For dogs, Carboplatin is typically dosed as follows — Used for osteosarcoma, transitional cell carcinoma, nasal tumors, and carcinomas: 300 mg/m² PO q3–4 weeks. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.

›What is the Carboplatin dose for cats?

For cats, Carboplatin is typically dosed as follows — Safe in cats — unlike cisplatin: 200–240 mg/m² IV q3–4 weeks. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.

›Does Carboplatin need a prescription?

Yes. Carboplatin is a prescription medication and should only be administered under veterinary supervision.

Educational reference only

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

Plumb's Veterinary Drug Handbook
Withrow & MacEwen's Small Animal Clinical Oncology
Merck Veterinary Manual
NRC Nutrient Requirements of Dogs and Cats
Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

ASPCA Animal Poison Control Center Guidelines
AAHA Diabetes Management Guidelines
ASPCA Poison Control Guidelines
RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

EPIC Study (J Vet Intern Med 2016)
JVIM FAT CAT Study

Regulatory & approvals — 1

CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

Washington State University VCPL MDR1 Database

Related medicines

Other medicines in the same class (Platinum-Based Chemotherapy).

Cisplatin

Alkylating-like agent that crosslinks DNA strands by forming platinum-DNA adducts, preventing DNA replication and transcription, leading to apoptosis. Cell-cycle non-specific.

dogcat