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Capromorelin

Prescription
Ghrelin Receptor Agonist / Appetite Stimulant
Last reviewed 21 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
2 available
Formulations
2

Mechanism of action

Synthetic ghrelin receptor (GHS-R1a) agonist that mimics the hunger hormone ghrelin, stimulating appetite via hypothalamic orexigenic pathways. Also stimulates growth hormone release from the pituitary. First FDA-approved appetite stimulant for dogs and cats.

At a glance

Class
Ghrelin Receptor Agonist / Appetite Stimulant
Schedule
Prescription
Storage
Store at room temperature; use within 6 months of opening

Dosing

🐕

Dog

FDA-approved for appetite stimulation in dogs
Dose
3 mg/kg
Route
PO
Frequency
q24h
🐈

Cat

FDA-approved for weight loss management in cats with CKD
Dose
2 mg/kg
Route
PO
Frequency
q24h
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Other — 2

Strength
Strength

Storage

Store at room temperature; use within 6 months of opening

Safety

Monitoring parameters

Body weight weekly initiallyFood intakeBUN/creatinine (cats with CKD)GI tolerance
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

No documented interactions.

Brands

Other markets

Entyce (dogs)
Elura (cats)

FAQs

Frequently asked questions

What is Capromorelin?
Capromorelin is a ghrelin receptor agonist / appetite stimulant used in pets. Synthetic ghrelin receptor (GHS-R1a) agonist that mimics the hunger hormone ghrelin, stimulating appetite via hypothalamic orexigenic pathways. Also stimulates growth hormone release from the pituitary. First FDA-approved appetite stimulant for dogs and cats.
What is Capromorelin used for in pets?
Capromorelin is used in veterinary medicine for: FDA-approved for appetite stimulation in dogs; FDA-approved for weight loss management in cats with CKD.
What is the Capromorelin dose for dogs?
For dogs, Capromorelin is typically dosed as follows — FDA-approved for appetite stimulation in dogs: 3 mg/kg PO q24h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Capromorelin dose for cats?
For cats, Capromorelin is typically dosed as follows — FDA-approved for weight loss management in cats with CKD: 2 mg/kg PO q24h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
Does Capromorelin need a prescription?
Yes. Capromorelin is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database
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