Calcium disodium ethylenediaminetetraacetic acid exchanges its calcium for heavy metals (lead, zinc, manganese, iron) with higher binding affinity, forming stable, water-soluble complexes that are excreted renally, reducing toxic metal body burden.
At a glance
Class
Heavy Metal Chelating Agent
Storage
Store at room temperature below 30°C
Dosing
Treatment for lead toxicity (most common heavy metal poisoning in pets)
Frequency
q6h (up to 5 days, then 5 days off before repeating)
Lead toxicity less common in cats but occurs
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Safety
BUN, creatinine, urinalysis q24–48hUrine lead levelsBlood lead levels before, during, after treatmentHydration status
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Interactions
No documented interactions.
Brands
Other markets
Calcium Disodium Versenate
FAQs
Frequently asked questions
›What is Calcium EDTA (CaEDTA)?
Calcium EDTA (CaEDTA) is a heavy metal chelating agent used in pets. Calcium disodium ethylenediaminetetraacetic acid exchanges its calcium for heavy metals (lead, zinc, manganese, iron) with higher binding affinity, forming stable, water-soluble complexes that are excreted renally, reducing toxic metal body burden.
›What is Calcium EDTA (CaEDTA) used for in pets?
Calcium EDTA (CaEDTA) is used in veterinary medicine for: Treatment for lead toxicity (most common heavy metal poisoning in pets); Lead toxicity less common in cats but occurs.
›What is the Calcium EDTA (CaEDTA) dose for dogs?
For dogs, Calcium EDTA (CaEDTA) is typically dosed as follows — Treatment for lead toxicity (most common heavy metal poisoning in pets): 25–27.5 mg/kg SQ/IV (diluted) q6h (up to 5 days, then 5 days off before repeating). Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Calcium EDTA (CaEDTA) dose for cats?
For cats, Calcium EDTA (CaEDTA) is typically dosed as follows — Lead toxicity less common in cats but occurs: 25 mg/kg SQ q6h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›Does Calcium EDTA (CaEDTA) need a prescription?
Yes. Calcium EDTA (CaEDTA) is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →References
References
The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.
Textbooks & handbooks — 5
- Plumb's Veterinary Drug Handbook
- Withrow & MacEwen's Small Animal Clinical Oncology
- Merck Veterinary Manual
- NRC Nutrient Requirements of Dogs and Cats
- Veterinary Pharmacology and Therapeutics (Riviere & Papich)
Clinical guidelines & consensus — 4
- ASPCA Animal Poison Control Center Guidelines
- AAHA Diabetes Management Guidelines
- ASPCA Poison Control Guidelines
- RECOVER CPR Guidelines
Journals & peer-reviewed studies — 2
- EPIC Study (J Vet Intern Med 2016)
- JVIM FAT CAT Study
Regulatory & approvals — 1
- CDSCO Veterinary Drug Approval Registry (1969–2026)
Databases — 1
- Washington State University VCPL MDR1 Database