Selective alpha-2 adrenergic receptor agonist that decreases aqueous humor production and increases uveoscleral outflow, reducing intraocular pressure. Also has neuroprotective effects on the optic nerve.
At a glance
Class
Alpha-2 Adrenergic Agonist (Ophthalmic)
Storage
Store at room temperature; discard 28 days after opening
Dosing
Used as adjunctive therapy for canine glaucoma
Cats are highly sensitive to systemic absorption of alpha-2 agonists — profound
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Safety
Intraocular pressureCardiovascular statusSedation levels (cats)
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →Interactions
No documented interactions.
FAQs
Frequently asked questions
›What is Brimonidine?
Brimonidine is a alpha-2 adrenergic agonist (ophthalmic) used in pets. Selective alpha-2 adrenergic receptor agonist that decreases aqueous humor production and increases uveoscleral outflow, reducing intraocular pressure. Also has neuroprotective effects on the optic nerve.
›What is Brimonidine used for in pets?
Brimonidine is used in veterinary medicine for: Used as adjunctive therapy for canine glaucoma; Cats are highly sensitive to systemic absorption of alpha-2 agonists — profound .
›What is the Brimonidine dose for dogs?
For dogs, Brimonidine is typically dosed as follows — Used as adjunctive therapy for canine glaucoma: undefined undefined Ophthalmic q8–12h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›What is the Brimonidine dose for cats?
For cats, Brimonidine is typically dosed as follows — Cats are highly sensitive to systemic absorption of alpha-2 agonists — profound : undefined undefined Ophthalmic q12h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
›Does Brimonidine need a prescription?
Yes. Brimonidine is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet.
Find a vet near you →References
References
The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.
Textbooks & handbooks — 5
- Plumb's Veterinary Drug Handbook
- Withrow & MacEwen's Small Animal Clinical Oncology
- Merck Veterinary Manual
- NRC Nutrient Requirements of Dogs and Cats
- Veterinary Pharmacology and Therapeutics (Riviere & Papich)
Clinical guidelines & consensus — 4
- ASPCA Animal Poison Control Center Guidelines
- AAHA Diabetes Management Guidelines
- ASPCA Poison Control Guidelines
- RECOVER CPR Guidelines
Journals & peer-reviewed studies — 2
- EPIC Study (J Vet Intern Med 2016)
- JVIM FAT CAT Study
Regulatory & approvals — 1
- CDSCO Veterinary Drug Approval Registry (1969–2026)
Databases — 1
- Washington State University VCPL MDR1 Database