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Azithromycin Ophthalmic

Prescription
Ophthalmic Macrolide Antibiotic
Last reviewed 22 Apr 2026 · PetCare.AI Editorial Team
Species
Dog, Cat
Brands
1 available
Formulations
1

Mechanism of action

Macrolide antibiotic in a polycarbophil mucoadhesive vehicle (DuraSite) that adheres to the ocular surface, providing sustained drug release. Binds 50S ribosomal subunit inhibiting protein synthesis. Also has anti-inflammatory properties.

At a glance

Class
Ophthalmic Macrolide Antibiotic
Schedule
Prescription
Storage
Store at room temperature; discard 14 days after opening

Dosing

🐕

Dog

Used for bacterial conjunctivitis, blepharitis, and Meibomian gland disease
Dose
Route
Ophthalmic
Frequency
q12–24h (see protocol)
🐈

Cat

NOT effective against Chlamydophila felis (intracellular — needs systemic doxycy
Dose
Route
Ophthalmic
Frequency
q12–24h
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Formulations

💊

Other — 1

Strength

Storage

Store at room temperature; discard 14 days after opening

Safety

Monitoring parameters

Clinical response at 5–7 daysCulture if no improvement
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

Interactions

No documented interactions.

Brands

United States

AzaSite
InSite Vision

FAQs

Frequently asked questions

What is Azithromycin Ophthalmic?
Azithromycin Ophthalmic is a ophthalmic macrolide antibiotic used in pets. Macrolide antibiotic in a polycarbophil mucoadhesive vehicle (DuraSite) that adheres to the ocular surface, providing sustained drug release. Binds 50S ribosomal subunit inhibiting protein synthesis. Also has anti-inflammatory properties.
What is Azithromycin Ophthalmic used for in pets?
Azithromycin Ophthalmic is used in veterinary medicine for: Used for bacterial conjunctivitis, blepharitis, and Meibomian gland disease; NOT effective against Chlamydophila felis (intracellular — needs systemic doxycy.
What is the Azithromycin Ophthalmic dose for dogs?
For dogs, Azithromycin Ophthalmic is typically dosed as follows — Used for bacterial conjunctivitis, blepharitis, and Meibomian gland disease: undefined undefined Ophthalmic q12–24h (see protocol). Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
What is the Azithromycin Ophthalmic dose for cats?
For cats, Azithromycin Ophthalmic is typically dosed as follows — NOT effective against Chlamydophila felis (intracellular — needs systemic doxycy: undefined undefined Ophthalmic q12–24h. Always consult your veterinarian for a dose tailored to your pet's weight, age, and condition.
Does Azithromycin Ophthalmic need a prescription?
Yes. Azithromycin Ophthalmic is a prescription medication and should only be administered under veterinary supervision.
Educational reference only
This information is provided for educational purposes and is not a substitute for professional veterinary advice, diagnosis, or treatment. Always consult a qualified veterinarian before administering any medication to your pet. Find a vet near you →

References

References

The PetCare.AI drug reference is built from 13 authoritative sources cited across 580 drug monographs.

Textbooks & handbooks — 5

  • Plumb's Veterinary Drug Handbook
  • Withrow & MacEwen's Small Animal Clinical Oncology
  • Merck Veterinary Manual
  • NRC Nutrient Requirements of Dogs and Cats
  • Veterinary Pharmacology and Therapeutics (Riviere & Papich)

Clinical guidelines & consensus — 4

  • ASPCA Animal Poison Control Center Guidelines
  • AAHA Diabetes Management Guidelines
  • ASPCA Poison Control Guidelines
  • RECOVER CPR Guidelines

Journals & peer-reviewed studies — 2

  • EPIC Study (J Vet Intern Med 2016)
  • JVIM FAT CAT Study

Regulatory & approvals — 1

  • CDSCO Veterinary Drug Approval Registry (1969–2026)

Databases — 1

  • Washington State University VCPL MDR1 Database
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